Psoriasis Flashcards

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1
Q

What is psoriasis?

A

A chronic inflammatory condition of the skin characterised by scaly erythematous and pruritic plaques

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2
Q

What are the 5 types of psoriasis?

A

Chronic plaque psoriasis
Flexural psoriasis
Guttate psoriasis
Pustular psoriasis
Generalised psoriasis

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3
Q

What is chronic plaque psoriasis?

A

Symmetrical plaques on the extensor surfaces of the limbs, scalp and back

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4
Q

What is flexural psoriasis?

A

Smooth erythematous plaques without scale in flexures

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5
Q

What is guttate psoriasis?

A

Multiple small, tear shaped lesions on the trunk after a streptococcal infection in children

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6
Q

What is pustular psoriasis?

A

Multiple petechiae and pustules on the palms and soles

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7
Q

What is generalised psoriasis?

A

Psoriasis with erythroderma and systemic illness

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8
Q

What are the risk factors for psoriasis?

A

Skin trauma
Withdrawal of steroids
Drugs
- NSAIDs
- Beta blockers
- Lithium
- Anti-malarials
Stress
Alcohol
Smoking
Cold/dry weather
Obesity
Family history

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9
Q

What signs are specific to psoriasis?

A

Auspitz sign
Koebner phenomenon
Residual pigmentation after lesions resolve

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10
Q

What is the auspitz sign?

A

Small points of bleeding when the plaques are scraped off

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11
Q

What is the Koebner phenomenon?

A

The development or psoriatic lesions in an area of skin affected by trauma

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12
Q

What is the first line topical treatment of psoriasis?

A

Topical corticosteroid and topical vitamin D applied at different times

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13
Q

What is the second line topical treatment of psoriasis?

A

After 4 weeks of first line treatment:
Continue topical treatment of vitamin D and corticosteroid for further 4 weeks

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14
Q

What is the third line topical treatment of psoriasis?

A

After a further 4 weeks of treatment:
Stop topical vitamin D
Apply corticosteroid twice daily

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15
Q

What is the first line systemic treatment of psoriasis?

A

Methotrexate

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16
Q

What is the second line systemic treatment of psoriasis?

A

Ciclosporin

17
Q

What biologics can be used to treat psoriasis?

A

Infliximab
Etanercept
Adalimumab

18
Q

What nail changes are seen in psoriasis?

A

Nailbed pitting
Onycholysis - separation of nail from nailbed
Subungual hyperkeratosis - thickening of nailbed

19
Q

What is the most common type of psoriasis?

A

Chronic plaque psoriasis

20
Q

How long should be left between courses of topcial corticosteroids?

A

4 weeks