protiens Flashcards

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1
Q

proteins are made of

A

amino acids

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2
Q

amino acid parts

A

amino group
carboxyl
single hydrogen
r group

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3
Q

amino acids are linked through

A

peptide bonds

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4
Q

n terminal

A

first amino acid in sequence

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5
Q

c terminal

A

last amino acid in sequence

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6
Q

protein shapes are due to

A

ionic bonds
hydrophobic bonds
hydrogen bonds
disulfide (cystine only)

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7
Q

primary protein structure

A

amino acid sequencese

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8
Q

secondary struc

A

interactions of gorup in peptide backbone

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9
Q

tertiary structure

A

folded shape of single polypeptide chain

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10
Q

quaternary structure

A

interactions bn multiple polypeptide subunits

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11
Q

secondary structure motifs

A

alpha helix
beta sheet

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12
Q

alpha helices

A

twisty i guess

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13
Q

beta sheets

A

antiparrallel
parallel

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14
Q

function determines

A

folding pattern

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15
Q

enzyme folding creates

A

activation sites

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16
Q

enzyme role

A

lower actvation energy for a reaction by binding to active site

17
Q

domain

A

independent folding region
more than 2nd, less than tertiary
like packets of structure

18
Q

how do proteins/ polypeptides interact

A

with h bonds, ionic bonds, and hydrophobic

19
Q

types of protein/ polypeptide interactions

A

surface surface
helix helix
surface string

20
Q

x ray crystallography

A

need protein crystal for the process
needs diffraction patter

21
Q

protein nmr

A

gets solution based structures
creates resonance peaks bn near neighbor atoms

22
Q

cryo EM

A

generate micorgrapahs of a protein
structure get resolved by computer refinements

23
Q

Alpha fold

A

ai protein structure generator
its accurate asf

24
Q

denaturation

A

protein structure melts and funciton is lost

25
Q

denaturation can be caused by

A

pH, temp, salt, hydration

26
Q

nucelotides

A

make up of nucleic acids such as DNA and RNA

27
Q

nucleotide fucntion

A

storgage, transmission, used of genetic info

28
Q

nucleotide units

A

sugar, phosphate, base

29
Q

nucelotides are linked with

A

phosphodiester bonds

30
Q

polynucleotide strands are (orientation)

A

antiparallel and complementary

31
Q

what forces hold ds DNA together

A

h bonds (base pairings)
hydrophobic forces (base stacking)

32
Q

RNA

A

less stable than DNA
usaly one stranded

33
Q

mRNA

A

provides codons for amino acid to be added to polypeptide

34
Q

tRNA

A

carries an amino acid that corresponds to the ribosome

35
Q

rRNA

A

part of the structure of the ribosome

36
Q
A