mroeeee stuff Flashcards

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1
Q

membrane

A

separates extracellular environment from intracellular

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2
Q

membrane allows for what to develop

A

gradients

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3
Q

membrane property

A

semi permeable barrier

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4
Q

membrane composition

A

asymmetrical environment
an association of phospholipids, and protiens

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5
Q

what type of amino acid typically bypasses the bilayer

A

hydrophobic

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6
Q

what do phospolipids spontaneously form

A

liposomes and bilayers

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7
Q

why are membranes energetically favorable

A

hydrophobic effect

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8
Q

inner leaflet

A

negative charge bc serine in
Phosphatidylserine and phosphatidylinositol

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9
Q

outter leaflet/ extracell leaflet features

A

Neutral/ positive
mostly glycolipids

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10
Q

bc of charge of membrane

A

membranes contribute a lot to migration of ions

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11
Q

membrane permeability what passes thru easy

A

small polar molecules

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12
Q

membrane permeability what passes thru easyish

A

small uncharged polar molecules

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13
Q

membrane permeability what passes thru harder

A

large macromolecules

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14
Q

membrane permeability what passes thru HARD

A

ions

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15
Q

membrane permeability is enhanced by

A

transporter and channel protein embeded in membrane

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16
Q

scramblases and flipase

A

speeds up the rate of smth flipping across membrane

17
Q

where are phosolipdis synthesized

A

in the cytomatic side of ER

18
Q

scramblases

A

move phospholipids to the cytosolic and lumen leaflets

19
Q

flippases

A

at golgi
separates specific types of phosphlipids to the cytosolic and lumen leaflets

20
Q

chemical changes to phosopholipid to make it more fluid

A

add double bond or make it sat

21
Q

Cholesterol

A

fluidity buffer in animal cells
at low temps, increases fluidity by reducing fatty acid interactions

22
Q

cholesterol at high temp

A

increases to fill in gaps from phospholipids moving too much
maintains fluidity

23
Q

lipid rafts

A

fatty acid chain that increases the thickness of the membrane in certain regions

24
Q

lipid rafts are home to

A

proteins involved in signaling or trafficking

25
Q

FRAP

A

flouresncene recovery after photobleaching

26
Q

protien funciton in membrane

A

enzymes, repectors, transporters, channels, anchors

27
Q

receptor

A

binds to molecules that activate the recpetor,
intracellualr signal

28
Q

transporters/channels

A

move molecules from one side to another

29
Q

anchors

A

attach to proteins on other cells and hold them together
attache to extracellular matrix
attach to intracellular cytoskeleton

30
Q

protien associate with membrane thru

A

hydrophobic interactions
amphipathic helices

31
Q

peripheral membrane protien

A

can release from membrane

32
Q

how many amino acids to span a layer

A

20

33
Q

aquaporin

A

alpha helix based channel protein that forms a pore (7)

34
Q

extracellular regions usally have

A

disulfide bonds

35
Q

extracellualr regions usally have - attached

A

carbos
glycoprotiens