mroeeee stuff Flashcards
membrane
separates extracellular environment from intracellular
membrane allows for what to develop
gradients
membrane property
semi permeable barrier
membrane composition
asymmetrical environment
an association of phospholipids, and protiens
what type of amino acid typically bypasses the bilayer
hydrophobic
what do phospolipids spontaneously form
liposomes and bilayers
why are membranes energetically favorable
hydrophobic effect
inner leaflet
negative charge bc serine in
Phosphatidylserine and phosphatidylinositol
outter leaflet/ extracell leaflet features
Neutral/ positive
mostly glycolipids
bc of charge of membrane
membranes contribute a lot to migration of ions
membrane permeability what passes thru easy
small polar molecules
membrane permeability what passes thru easyish
small uncharged polar molecules
membrane permeability what passes thru harder
large macromolecules
membrane permeability what passes thru HARD
ions
membrane permeability is enhanced by
transporter and channel protein embeded in membrane
scramblases and flipase
speeds up the rate of smth flipping across membrane
where are phosolipdis synthesized
in the cytomatic side of ER
scramblases
move phospholipids to the cytosolic and lumen leaflets
flippases
at golgi
separates specific types of phosphlipids to the cytosolic and lumen leaflets
chemical changes to phosopholipid to make it more fluid
add double bond or make it sat
Cholesterol
fluidity buffer in animal cells
at low temps, increases fluidity by reducing fatty acid interactions
cholesterol at high temp
increases to fill in gaps from phospholipids moving too much
maintains fluidity
lipid rafts
fatty acid chain that increases the thickness of the membrane in certain regions
lipid rafts are home to
proteins involved in signaling or trafficking
FRAP
flouresncene recovery after photobleaching
protien funciton in membrane
enzymes, repectors, transporters, channels, anchors
receptor
binds to molecules that activate the recpetor,
intracellualr signal
transporters/channels
move molecules from one side to another
anchors
attach to proteins on other cells and hold them together
attache to extracellular matrix
attach to intracellular cytoskeleton
protien associate with membrane thru
hydrophobic interactions
amphipathic helices
peripheral membrane protien
can release from membrane
how many amino acids to span a layer
20
aquaporin
alpha helix based channel protein that forms a pore (7)
extracellular regions usally have
disulfide bonds
extracellualr regions usally have - attached
carbos
glycoprotiens