Proteins

Question 1

Proteins can be both soluble and insoluble. Give an example of both.

Answer 1

Soluble: blood plasma proteins
Insoluble: collagen

Question 2

Why are proteins important

Answer 2

the cell communicates via protein interactions, binding sites, and signaling molecules. Adhering specific proteins to the surface of a material can induce a specific behavior from a protein.

Question 3

Vroman Effect

Answer 3

proteins that have higher mobility will adhere to a surface first, due to diffusion principles and kinetics, however, later, proteins with a higher affinity to the surface will displace other proteins. (thermodynamic)

Question 4

Adsorption Isotherm

Answer 4

there are roughly two phases, a rapid diffusion controlled stage, followed by a second slower surface controlled phase.

Question 5

RGD

Answer 5

a protein that Arg-Gly-Asp that interacts with fibronectin for integrin binding to the ECM.