Final (Difficult Concepts) Flashcards

1
Q

Temporal Host Response: Order (6)

A

PMNs, MCs, Macrophages, FBGC, Fibroblasts, Fibrosis

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2
Q

PMN climax

A

12h, first

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3
Q

MC climax

A

24h

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4
Q

Innate Immune Response (4 components)

A

epithelial cells, phagocytes, complement system, NK cells

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5
Q

Adaptive Immune Response (4 components)

A

B lymphocytes, antibodies, T lymphocytes, effector T cells

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6
Q

NK cells

A

Natural killer cells, innate immunity

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7
Q

B lymphocytes

A

cell in the adaptive immunity response that has proteins on its surface that are SPECIFIC binding

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8
Q

T lymphocytes

A

cell in adaptive immunity response with specific T receptors

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9
Q

Intrinsic Pathway (6)

A

(XII–>XIIa)(XI–>XIa)(IX–>IXa with Ca++)(Ca++ VIII Platelets)(X–>Xa)

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10
Q

Extrinsic Pathway(3)

A

(VII–>VIIa)(Ca++ Tissue Factor)(X–>Xa)

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11
Q

Common Pathway: 1

A

X–>Xa

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12
Q

Common Pathway: 2

A

Xa turns Prothrombin to thrombin with the help of Ca++ and V platelets

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13
Q

Common Pathway: 3

A

Thrombin both turns XIII–>XIIIa and fibrinogen to fibrin polymer

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14
Q

Common Pathway: 4

A

XIIIa turns Fibrin polymer into Fibrin stable polymer

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15
Q

Platelets on Artificial Surfaces: 1

A

Proteins adsorb onto biomaterial

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16
Q

Platelets on Artificial Surfaces: 4 components of adsorbed proteins

A

TxA2, ADP, Thrombin, and PF4/BetaTG

17
Q

Platelets on Artificial Surfaces: Thrombin turns ___ into ___

A

fibrinogen into fibrin

18
Q

Frustrated phagocytosis (3)

A

monocyte–>macrophage–>FBGC