Final (Difficult Concepts) Flashcards
Temporal Host Response: Order (6)
PMNs, MCs, Macrophages, FBGC, Fibroblasts, Fibrosis
PMN climax
12h, first
MC climax
24h
Innate Immune Response (4 components)
epithelial cells, phagocytes, complement system, NK cells
Adaptive Immune Response (4 components)
B lymphocytes, antibodies, T lymphocytes, effector T cells
NK cells
Natural killer cells, innate immunity
B lymphocytes
cell in the adaptive immunity response that has proteins on its surface that are SPECIFIC binding
T lymphocytes
cell in adaptive immunity response with specific T receptors
Intrinsic Pathway (6)
(XII–>XIIa)(XI–>XIa)(IX–>IXa with Ca++)(Ca++ VIII Platelets)(X–>Xa)
Extrinsic Pathway(3)
(VII–>VIIa)(Ca++ Tissue Factor)(X–>Xa)
Common Pathway: 1
X–>Xa
Common Pathway: 2
Xa turns Prothrombin to thrombin with the help of Ca++ and V platelets
Common Pathway: 3
Thrombin both turns XIII–>XIIIa and fibrinogen to fibrin polymer
Common Pathway: 4
XIIIa turns Fibrin polymer into Fibrin stable polymer
Platelets on Artificial Surfaces: 1
Proteins adsorb onto biomaterial