Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Biomaterials > Final (Simple Concepts) > Flashcards

Final (Simple Concepts) Flashcards

1
Q

Thrombis (Def)

A

blood clot obstructing flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Platelet Adhesion: vWFs

A

a platelet adhesion protein: Von Wilebrand Factor, blood glycoprotein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Platelet Adhesion: Fn

A

fibronectin: heavy glycoprotein that binds extracellular matrix components

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Extrinsic Pathway

A

tissue factor pathway that provides a quick burst of thrombin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Intrinsic Pathway

A

contact activation… minor role in clot formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Fibrinolysis

A

breakdown of clot formations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Host Foreign Body Response: Also known as ___ ___.

A

Wound Healing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Wound Healing: inflammation: specific or nonspecific?

A

nonspecific

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Objectives of wound healing

A

destroy foreign objects, and promote regeneration and formation of fibroblastic scar tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Dedifferentiation

A

when a cell must revert back to a prior state before being able to change form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Transdifferentiation

A

when a mature cell does not need to revert back to a prior state to change form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Innate Immune Response

A

Quick, nonspecific

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Adaptive Immune Response

A

Slower, specific

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Antibody structure: Fab region

A

interacts with antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Antibody structure: Fc region

A

classifies types of immunoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Function of complement cascade(4)

A

Cell lysis, phagocytosis, Mast cell activation and PMN reciting, immune complex solubilization

17
Q

Cytokines: IL-1 (3 functions)

A

Cell activation of T,B,NK ; leukocyte adherence to endothelial cells ; fibroblasts collagen synthesis

18
Q

Cytokines: IL-4 (4 functions)

A

Prolif/Diff of B cells; isotype switching; mast and T cell proliferation; antagonistic with INF gamma

19
Q

Cytokines: IL-10 (2 functions)

A

Immunosuppression; inhibits cytokine expression

20
Q

Cytokines: GM-CSF (1 function)

A

Prolif/Activation of PMNs and monocytes from bone marrow

21
Q

PMNs

A

polymorphonuclear leukocytes

22
Q

monocytes

A

eventually become macrophages

23
Q

neutrophils

A

base of the innate immune system

24
Q

Tox/Hyper: (description, participants, time, material): Type 1

A

immediate, IgE, histamine, heparin

25
Q

IgE

A

immunoglobulin: triggers mast cell release that starts allergic pathway

26
Q

heparin

A

thins blood

27
Q

Tox/Hyper: (description, participants, time, material): Type 2

A

cytotoxic, IgG IgM, platelet activation, time n/a, reported with biomaterials

28
Q

Tox/Hyper: (description, participants, time, material): Type 3

A

immune complex mediated, antigen/antibody reaction, days to weeks, NOT common to biomaterials

29
Q

Tox/Hyper: (description, participants, time, material): Type 4

A

cell mediated, antigen Tcells cytokines, delayed, metal and acrylics

30
Q

Material Centered Infection: what controls bacterial adhesion and colonization?

A

Van der Waals, hydrophobicity, pre-adsorbed proteins

31
Q

Competition surface interaction includes (3)

A

bacteria, host cells, and proteins

32
Q

Biofilms: what kind of coating, and what kind of resistance?

A

polysaccharide coating with antibiotic resistance

33
Q

BioCharMethods: Radioimmunoassay/ELISA

A

Used to characterize how much of an antibody exists, or how much protein is bound by a specific antibody

34
Q

BioCharMethods: Immunoprecipitation

A

Used to precipitate a specific protein out of solution by using an antibody that specifically binds to that protein

35
Q

BioCharMethods: Western Blotting

A

Proteins separated using gel electrophoresis, then a dyed antibody is added so that you can see the amount of that specific protein on a piece of paper

36
Q

BioCharMethods: FACS(Fluorescence activated cell sorting)

A

Used to separate different biological cells by using light scattering and fluorescent properties of each cell. These cells can be tagged with charges and put through an electric ring to physically separate them.

37
Q

BioCharMethods: Histology

A

microscopic anatomy of biologic molecules

38
Q

BioCharMethods: Scanning electron microscopy

A

uses an electron beam to produce an image of surface of a material.

Biomaterials (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions