proteins Flashcards

1
Q

rich in tryptophan

A

prealbumin

transthyretin

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2
Q

confirm CSF specimen

A

prealbumin

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3
Q

metabolize vitamin A

A

prealbumin

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4
Q

most abundant protein in normal plasma

A

albumin

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5
Q

maintains oncotic pressure

A

albumin

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6
Q

rises in dehydration

A

albumin

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7
Q

general transport and carrier protein

A

albumin

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8
Q

vital in the understanding and interpretation of calcium and magnesium because they are bound to it

A

albumin

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9
Q

related to emphysema

A

alpha1-antitrypsin

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10
Q

neutralize elastase

A

alpha1-antitrypsin

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11
Q

seen in maternal blood 7-8mos of pregnancy

A

alpha1-fetoprotein (AFP)

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12
Q

increased in spina bifida and neural tube defects

A

alpha1-fetoprotein (AFP)

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13
Q

decreased in down and edwards syndrome

A

alpha1-fetoprotein (AFP)

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14
Q

has a very high carbohydrate and sialic content

A

oromucosoid

alpha1-glycoprotein

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15
Q

greatest affinity for progesterone

A

oromucosoid

alpha1-glycoprotein

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16
Q

distinguish intravascular (low) and extravascular hemolysis (normal)

A

haptoglobin

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17
Q

bind free Hgb

A

haptoglobin

18
Q

transports ferric ions

A

transferrin

siderophilin

19
Q

determines TIBC

A

transferrin

20
Q

copper-binding protein

A

ceruloplasmin

21
Q

imparts blue color to the protein

A

ceruloplasmin

22
Q

decreased in Wilson’s disease

A

ceruloplasmin

24
Q

has the strongest binding affinity for heme

25
marker for assessing disease activity in rheumatic disorders
C3 | complement
26
27
most abundant of the coagulation factors
fibrinogen
28
high levels in plasma may cause increase in ESR
fibrinogen
29
30
rapid test for presumptive bacterial versus viral infection
CRP | high - bacterial, low - viral
31
what does Kjedahl measure?
nitrogen content
32
method with this principle: formation of violet-colored chelate between cupric ions and peptide bonds
biuret method
33
what does Nessler and Berthelot measure?
ammonia
34
what keeps copper in the solution during biuret?
tartrate salt
35
antioxidant and stabilizer of copper in biuret
potassium iodide
36
most specific dye to albumin
bomcresol purple
37
gold standard for total protein measurement
Kjedahl
38
reference method for total protein measurement
biuret method
39
# true or false high ionic strength = low migration
true
40
protein that migrates the slowest but has the highest pI
gamma globulins