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Clinical Chemistry > proteins > Flashcards

proteins Flashcards

1
Q

rich in tryptophan

A

prealbumin

transthyretin

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2
Q

confirm CSF specimen

A

prealbumin

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3
Q

metabolize vitamin A

A

prealbumin

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4
Q

most abundant protein in normal plasma

A

albumin

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5
Q

maintains oncotic pressure

A

albumin

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6
Q

rises in dehydration

A

albumin

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7
Q

general transport and carrier protein

A

albumin

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8
Q

vital in the understanding and interpretation of calcium and magnesium because they are bound to it

A

albumin

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9
Q

related to emphysema

A

alpha1-antitrypsin

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10
Q

neutralize elastase

A

alpha1-antitrypsin

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11
Q

seen in maternal blood 7-8mos of pregnancy

A

alpha1-fetoprotein (AFP)

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12
Q

increased in spina bifida and neural tube defects

A

alpha1-fetoprotein (AFP)

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13
Q

decreased in down and edwards syndrome

A

alpha1-fetoprotein (AFP)

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14
Q

has a very high carbohydrate and sialic content

A

oromucosoid

alpha1-glycoprotein

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15
Q

greatest affinity for progesterone

A

oromucosoid

alpha1-glycoprotein

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16
Q

distinguish intravascular (low) and extravascular hemolysis (normal)

A

haptoglobin

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17
Q

bind free Hgb

A

haptoglobin

18
Q

transports ferric ions

A

transferrin

siderophilin

19
Q

determines TIBC

A

transferrin

20
Q

copper-binding protein

A

ceruloplasmin

21
Q

imparts blue color to the protein

A

ceruloplasmin

22
Q

decreased in Wilson’s disease

A

ceruloplasmin

23
Q
A
24
Q

has the strongest binding affinity for heme

A

hemopexin

25
Q

marker for assessing disease activity in rheumatic disorders

A

C3

complement

26
Q
A
27
Q

most abundant of the coagulation factors

A

fibrinogen

28
Q

high levels in plasma may cause increase in ESR

A

fibrinogen

29
Q
A
30
Q

rapid test for presumptive bacterial versus viral infection

A

CRP

high - bacterial, low - viral

31
Q

what does Kjedahl measure?

A

nitrogen content

32
Q

method with this principle: formation of violet-colored chelate between cupric ions and peptide bonds

A

biuret method

33
Q

what does Nessler and Berthelot measure?

A

ammonia

34
Q

what keeps copper in the solution during biuret?

A

tartrate salt

35
Q

antioxidant and stabilizer of copper in biuret

A

potassium iodide

36
Q

most specific dye to albumin

A

bomcresol purple

37
Q

gold standard for total protein measurement

A

Kjedahl

38
Q

reference method for total protein measurement

A

biuret method

39
Q

true or false

high ionic strength = low migration

A

true

40
Q

protein that migrates the slowest but has the highest pI

A

gamma globulins

Clinical Chemistry (4 decks)

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