proteins Flashcards
rich in tryptophan
prealbumin
transthyretin
confirm CSF specimen
prealbumin
metabolize vitamin A
prealbumin
most abundant protein in normal plasma
albumin
maintains oncotic pressure
albumin
rises in dehydration
albumin
general transport and carrier protein
albumin
vital in the understanding and interpretation of calcium and magnesium because they are bound to it
albumin
related to emphysema
alpha1-antitrypsin
neutralize elastase
alpha1-antitrypsin
seen in maternal blood 7-8mos of pregnancy
alpha1-fetoprotein (AFP)
increased in spina bifida and neural tube defects
alpha1-fetoprotein (AFP)
decreased in down and edwards syndrome
alpha1-fetoprotein (AFP)
has a very high carbohydrate and sialic content
oromucosoid
alpha1-glycoprotein
greatest affinity for progesterone
oromucosoid
alpha1-glycoprotein
distinguish intravascular (low) and extravascular hemolysis (normal)
haptoglobin
bind free Hgb
haptoglobin
transports ferric ions
transferrin
siderophilin
determines TIBC
transferrin
copper-binding protein
ceruloplasmin
imparts blue color to the protein
ceruloplasmin
decreased in Wilson’s disease
ceruloplasmin
has the strongest binding affinity for heme
hemopexin
marker for assessing disease activity in rheumatic disorders
C3
complement
most abundant of the coagulation factors
fibrinogen
high levels in plasma may cause increase in ESR
fibrinogen
rapid test for presumptive bacterial versus viral infection
CRP
high - bacterial, low - viral
what does Kjedahl measure?
nitrogen content
method with this principle: formation of violet-colored chelate between cupric ions and peptide bonds
biuret method
what does Nessler and Berthelot measure?
ammonia
what keeps copper in the solution during biuret?
tartrate salt
antioxidant and stabilizer of copper in biuret
potassium iodide
most specific dye to albumin
bomcresol purple
gold standard for total protein measurement
Kjedahl
reference method for total protein measurement
biuret method
true or false
high ionic strength = low migration
true
protein that migrates the slowest but has the highest pI
gamma globulins