Protein synthesis inhibitors spectrums

Question 1

Spectrum of linezolid:

Answer 1

Gram +, inclunding MRSA, VRE

Question 2

Spectrum of aminoglycosides:

Answer 2

Gram -, aerobic

***require lots of energy to enter cell

can’t get into cell in G+ anaerobes but can be given w/cell wall inhibitor like 3rd gen cephalosporins

Question 3

Spectrum of tetracyclines:

Answer 3

Broad, but due to resistance:

B. burdorferi (lyme’s disease

H. pylori

Mycoplasma pneumoniae

Question 4

Spectrum of macrolides:

Answer 4

Broad coverage of respiratory pathogens

chlamydia (single dose)

Question 5

Spectrum of Chloramphenicol:

Answer 5

Extended but use is limited due to severe side effects

TOXIC

Question 6

Spectrum of clindamycin:

Answer 6

Gram +, anaerobic

acne

Question 7

Spectrum of quinupristin/dalfopristin (streptogramins):

Answer 7

reserved for MULTIDRUG RESISTANT G+