Protein synthesis Flashcards

1
Q

What enzyme matches amino acids to tRNA?

A

-aminoacyl tRNA synthetase

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2
Q

What are the ribosomal subunits in eukaryotes?

Prokaryotes?

A
  • 60s and 40s –> 80s

- 50s and 30s –> 70s

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3
Q

what enzyme transfers amino acids on P site to the amino acid on the A site?

A

peptidyltransferase

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4
Q

where is peptidyltransferase located in prokaryotes?

A

-in 23s portion of 50s subunit

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5
Q

What does translocation (moving the mRNA down the ribosome) requires in prokaryotes?
in eukaryotes?

A
  • Elongation factor G

- EF-2

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6
Q

What toxins inhibit EF-2 in eukaryotes?

A
  • diphtheria toxin

- Exotoxin A (pseudomonas)

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