Protein synthesis Flashcards
1
Q
What enzyme matches amino acids to tRNA?
A
-aminoacyl tRNA synthetase
2
Q
What are the ribosomal subunits in eukaryotes?
Prokaryotes?
A
- 60s and 40s –> 80s
- 50s and 30s –> 70s
3
Q
what enzyme transfers amino acids on P site to the amino acid on the A site?
A
peptidyltransferase
4
Q
where is peptidyltransferase located in prokaryotes?
A
-in 23s portion of 50s subunit
5
Q
What does translocation (moving the mRNA down the ribosome) requires in prokaryotes?
in eukaryotes?
A
- Elongation factor G
- EF-2
6
Q
What toxins inhibit EF-2 in eukaryotes?
A
- diphtheria toxin
- Exotoxin A (pseudomonas)