PROTEIN SYNTHESIS Flashcards
through this, the “working copies” of DNA is expressed through transcription and then further translated
RNA
does not contain equal amounts of specific bases and molecules
RNA
types of RNA
hnRNA
snRNA
mRNA
rRNA
tRNA
hnRNA
HETEROGENOUS NUCLEAR RNA
snRNA
SMALL NUCLEAR RNA
mRNA
MESSENGER RNA
rRNA
RIBOSOMAL RNA
tRNA
TRANSFER RNA
type of RNA that directly by DNA transcription
hnRNA
type of RNA wherein post-transcription processing converts heterogenous nuclear RNA to messenger RNA
hnRNA
type of RNA that facilitates the conversion of heterogenous nuclear RNA to messenger RNA
snRNA
type of RNA that contains from 100 - 200 nucleotides
snRNA
type of RNA that carries genetic information to the site for protein synthesis
mRNA
type of RNA that combines with specific proteins to form ribosomes
mRNA
type of RNA that has the most abundant type of RNA in a cell
rRNA
percentage of rRNA in a cell
75% - 80%
type of RNA that delivers amino acids to the sites for protein synthesis
tRNA
type of RNA that are smallest of the RNAs and possess only 75-90 nucleotide units
tRNA
process by which DNA directs synthesis of hnRNA or mRNA molecules that carry code information needed for protein synthesis
TRANSCRIPTION
short segment of DNA strand that contains instructions for formation of specific hnRNA/mRNA
GENE
segment of a DNA strand that contains the base sequence for production of specific hnRNA/mRNA
GENE
genes are composed of how many units of nucleotide
1000-3500
all of the genetic material / total DNA contained in the chromosomes of an organism
GENOME
strand of DNA used for hnRNA/mRNA synthesis
TEMPLATE STRAND
the other DNA strand that gives the base sequence present in the hnRNA strand being synthesized
INFORMATIONAL STRAND
precursor of mRNA
hnRNA
RNA produced from a gene through transcription
hnRNA
expression of genetic information
EXON
gene segment that conveys or codes for genetic info
EXON
interruption of genetic information
INTRON
gene segment that does not convey or codes for genetic information
INTRON
process of removing introns from an hnRNA molecule and joining remaining exons to form mRNA molecule
SPLICING
snRNPs (small nuclear ribonucleoprotein particle)
“snurps”
large assembly of snRNA molecules and proteins involved in the conversion of hnRNA molecules to mRNA molecules
SPLICEOSOMES
process which several different proteins that are variations of a basic structural motif can be produced from a single gene
ALTERNATIVE SPLICING
all of mRNA molecules that can be generated from the genetic material in a genome
TRANSCRIPTOME
assignment of 64 mRNA codons to specific amino acids
GENETIC CODE
how many mRNA codons are there in a/the genetic code
64
three-nucleotide sequence in an mRNA molecule that codes for a specific amino acid
CODON
known to be highly degenerate and many amino acids are designated by more than one codon
GENETIC CODE TABLE
amino acids with only a single codon
MET & TRP
Methionine and Tryptophan
initiation codon
AUG
Met|hionine
stop codons
UAG
UAA
UGA
loop opposite of the open end of the cloverleaf and is the site for a sequence of three bases
ANTICODON
three-nucleotide sequence on a tRNA molecule that is complementary to a codon on an mRNA molecule
ANTICODON
ability of certain anticodons to pair with codons that differ at third base
WOBBLE
process by which mRNA codons are deciphered and a particular protein molecule is synthesized
TRANSLATION
substances needed for the translation phase of protein synthesis
mRNA
tRNA
amino acids
ribosomes
number of different enzymes
rRNA-protein complex that serves as site for translation phase of protein synthesis
RIBOSOMES
five general steps to the translation process
1) activation of tRNA
2) initiation
3) elongation
4) termination
5) post-translational processing
P site is also known
peptidyl site
A site
aminoacyl site
part of translation where ribosomes moves down an mRNA molecule three base position so that a new codon can occupy the ribosomal subunit
TRANSLOCATION
step in the translation phase where amino acid interacts with ATP to become highly energized
STEP 1: ACTIVATION OF tRNA
step in the translation phase wherein mRNA attaches to ribosome so that first codon is at P site
STEP 2: INITIATION
step in the translation phase wherein another tRNA with second amino acid binds at the A site
STEP 3: ELONGATION
step in the translation phase wherein the polypeptide chain continues to lengthen until stop codon appears
STEP 4: TERMINATION
step in the translation phase wherein during the post-translation processing, the cleavage of Met usually occurs
STEP 5: POST-TRANSLATION PROCESSING