ANTIBIOTIC to MUTATION Flashcards

1
Q

TRUE/FALSE:
human ribosomes are smaller than bacterial ribosomes

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

TRUE/FALSE:
bacterial ribosomes are larger than human ribosomes

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

TRUE/FALSE:
human ribosomes are much larger than bacterial ribosomes

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

initiator codon of bacteria

A

N-FORMYLMETHIONINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

TRUE/FALSE:
in humans, mRNA begins while being transcribed from DNA

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

TRUE/FALSE:
in bacteria, mRNA begins while being transcribed from DNA

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

TRUE/FALSE:
in humans, mRNA translation begins only after transcription

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

TRUE/FALSE:
in bacteria, mRNA translation begins only after transcription

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

HUMAN/BACTERIA:
mRNA translation begins only after transcription

A

HUMAN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

HUMAN/BACTERIA:
mRNA begins while being transcribed from DNA

A

BACTERIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

HUMAN/BACTERIA:
very little processing time after being transcribed and very-short lived

A

BACTERIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

HUMAN/BACTERIA:
mRNA undergoes considerable processing before mature RNA is formed

A

HUMAN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

name the five antibiotics

A

ERYTHROMYCIN
TERRAMYCIN
STREPTOMYCIN
NEOMYCIN
CHLORAMPHENICOL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

type of antibiotics that binds larger bacterial ribosomes subunit

A

ERYTHROMYCIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

type of antibiotics that blocks the exit of a growing peptide chain

A

ERYTHROMYCIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

type of antibiotics that blocks the A-site location on the ribosome

A

TERRAMYCIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

type of antibiotics that prevents the attachment of amino-acid carrying tRNAs

A

TERRAMYCIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

type of antibiotics that binds to the smaller bacterial ribosome subunit causing a shape change and causes a misreading of mRNA info

A

STREPTOMYCIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

type of antibiotics that bind to smaller bacterial ribosomes subunit and is similar to streptomycin

A

NEOMYCIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

type of antibiotics that binds to ribosome and interferes with formation of peptide bonds between amino acids

A

CHLORAMPHENICOL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

error in base sequence in a gene that is reproduced during DNA replication and alters genetic info that is passed on during transcription

22
Q

substance or agent that causes change in structure of gene

23
Q

types of mutation

A

GENE/DNA
CHROMOSOME

24
Q

permanent alteration in the DNA sequence that makes up a gene

A

GENE/DNA MUTATION

25
alterations that affects whole chromosomes and whole genes rather than just individual nucleotide
CHROMOSOME MUTATION
26
classification of gene/dna mutation
POINT FRAMESHIFT
27
classification of substitution
SILENT NONSENSE MISSENSE
28
classfication of missense mutation
CONSERVATIVE NONCONSERVATIVE
29
classification of frameshift mutation
INSERTION DELETION
30
classification of chromosome mutation
INVERSION DELETION DUPLICATION TRANSLOCATION
31
mutation in which one base in DNA base sequence is replaced with another base
POINT MUTATION
32
one base is incorrectly added during replication and replaces the pair in the corresponding position on the complementary strand
SUBSTITUTION
33
sub-classification of substitution code for the same amino acid / "synonymous substitution"
SILENT MUTATION
34
sub-classification of substitution does not affect the functioning of the protein
SILENT MUTATION
35
sub-classification of substitution when base substitution result in a stop codon ultimately truncating translation and leads to a nonfunctional protein
NONSENSE MUTATION
36
sub-classification of substitution that has a change in one DNA base pair that result in substitution of one amino acid for another in the protein made by a gene
MISSENSE
37
sub-classification of missense mutation that results in an amino acid change but the properties of amino acid stay the same
CONSERVATIVE MISSENSE
38
sub-classification of missense mutation that results in amino acid change that has different properties than the wild type
NONCONSERVATIVE MISSENSE
39
sub-classification of missense mutation wherein protein may lose its function which results in disease of the organism
NONCONSERVATIVE MUTATION
40
a type of mutation that occurs when the addition or loss of DNA bases changes a gene's reading frame
FRAMESHIFT MUTATION
41
consists of groups of 3 bases that each code for one amino acid
READING FRAME
42
shift the grouping of the reading frame and changes the code for amino acids
FRAMESHIFT MUTATION
43
a type of frameshift mutation where one or more extra nucleotides are inserted or added into the replicating DNA
INSERTION
44
a type of frameshift mutation where protein made by the gene may not function properly
INSERTION
45
a type of frameshift mutation that changes the number of DNA bases by removing pieces of DNA
DELETION
46
a type of frameshift mutation where small deletions may remove one or a few base pairs within a gene while larger deletions can remove an entire gene
DELETION
47
a type of frameshift mutation where the deleted DNA may alter the function of the resulting proteins
DELETION
48
a type of chromosome mutation wherein a region of chromosome is lost and results in the absence of all genes in that area
DELETION
49
a type of chromosome mutation wherein a region from one chromosome is aberrantly attached to another chromosome
TRANSLOCATION
50
a type of chromosome mutation wherein a region of a chromosome is repeated, resulting in an increase in dosage from the genes in that region
DUPLICATION
51
a type of chromosome mutation wherein one region of a chromosome is flipped and reinserted
INVERSION