Protein, exercise & hunger Flashcards
Muscle growth/loss measurements (2)
Fractional synthetic rate (FSR)
Fractional breakdown rate
FBR
What does exercise do to MPS & MPB
at rest MPN > MPS
increases both
- MPB response up less and stays elevated for less time
What happens to net balance following exercise
net balance because less negative (up to 48h for untrained)
Intensity - MPS relationship
^ intensity = ^ MPS (where work matched)
- when lifting to failure all muscle fibres are activated increasing MPS further
training responses related to FSR & FBR (fasted)
Both ^ FSR (more in ut)
only ut ^ FBR
Why does the type of training produce such different phenotype results
different rates of PB, PS of mitochondrial, sarcoplasmic, myofibrillar proteins
training responses related to FSR & FBR (fed)
Trained leg had higher initial response but it wasn’t as prolonged
What happens as you train
as you get use to resistance exercise your response comes more specific
AA (nutritional protein) has what effect on MPS
Increase (at rest & exercise)
= positive net balance
Muscle protein balance over a day (graph)
Wake up - negative breakfast - positive - negative lunch - positive - negative dinner - positive
what effect does exercise have on the muscle protein balance graph
smaller dips bigger peaks (over all more positive balance = ^ muscle mass)
Appetite and hunger differences
Appetite - desire to eat (external/psych factors)
Hunger - internal drive to eat (central - hypothalamus, peripheral - blood glucose)
Energy regulating hormone examples
CCK - decrease
Peptide PPY - decrease
excess glucocorticoids -
increase
Ghrelin - increase
What does Ghrelin (hormone) do?
An appetite stimulant - meal initiator
Lower in obese, higher when dieting
Acylated form = active
How does Ghrelin (hormone) work?
- Released from empty stomach
- travels to hypothalamus
- Neuropeptide Y release = makes you eat
- eating suppresses ghrelin release
