Protein and Amino Acid and Enzymes Flashcards
primary structure
amino acids– covalent bonds
secondary structure
hydrogen bond
alpha helices and beta pleated sheets
tertiary structure
ionic bonds, dipole-dipole, london dispersion and covalent interaction between amino acids
quaternary structure
disulfide bonds, london dispersion, dipole dipole,
what do kinase proteins do
they phosphorylate proteins
What properties exist for tyrosin
polar aromatic
which amino acid codes the start codon
methonine
how to determine the pI of a structure
Pka1+Pka2/2
what is a stereocenter
an atom that is bonded to 4 different subsitutents (chiral atom)
what is the only achiral amino acid
glycine (Gly, G) hydrophobic
what is average molecular weight of amino acid
110Da
what is a zymogen
active upon cleavage or modificaton
what does competitive inhibitor do to kinetics
increase Km, does not change V max
at low substrate addition of more substrate will
increase the rate linearly as it approaches vmax it will increase non linearly, but will not effect rate or vmax when reached
how are cyestine disulfide bridge formed or broken
REDOX
What is the termination process in protein synthesis
STOP codon–> release factors officially end protein synthesis
what does noncompetitive inhibitors do to enzyme kinetics
do not change the Km though they do decrease the Vmax
how do you calculate pI?
the average of the Pka values
how to identify a stereocenter
attached to 4 unique molecular groups
what is an achiral amino acid
glycine
