Prostatis & Incompotence

Question 1

What is prostatitis?

Answer 1

Inflammation of the prostate gland

2 types:
• bacterial
• abacterial (chronic pelvic pain)

Question 2

Is bacterial prostatitis caused by gram positive or gram negative?

Answer 2

Gram negative
E.g. E.coli

Question 3

Are leukocytes found in urine in abacterial prostatitis?

Answer 3

Yes
But no pathogens

Question 4

Symptoms of acute and chronic prostatitis?

Answer 4

Acute:
• dysuria
• increased frequency of urinating

Chronic:
• pelvic pain
• milder symptoms than acute

Question 5

Treatment of acute and chronic prostatitis?

Answer 5

Acute bacterial prostatitis:
Quinolone

Chronic abacterial prostatitis:
Alpha blocker & antibiotic

All patients:
• Paracetamol/ibuprofen
• laxative (if stool is pressing on rectum)

Question 6

Quinolone MOA

Answer 6

Inhibits activity of DNA & Topoisiomerase

Question 7

What is Erectile dysfunction?

Answer 7

Inability to get or main an erection, that is enough for sexual intercourse

Question 8

What are the Contributing physiological & contributing factors?

Answer 8

Physiological
• depression
• anxiety
• excess alcohol
• history of psychological abuse

Drugs:
• marijuana
• methadone
• alcohol
• cocaine

Question 9

Pharmacological options ?

Answer 9

Phosphodiesterase type-inhibitors (type 5)
MOA: increases blood flow to penis
Examples:
• Avanafil
• tadalafil - longer acting
• slidenafil

Question 10

Second line?

Answer 10

Alprostadil
MOA: prostaglandin E1analogue

Question 11

OTC Medicine ?

Answer 11

Slidenafil - viagra connect
Tadalafil

Question 12

Premature ejaculation?

Answer 12

Brief sextual latency, loss of control and physiological distress

Question 13

Pharmacological treatment?

Answer 13

Dapoxetine
MOA: SSRI