Prostate + Testicular cancer

Question 1

What is the usual initial investigation for testicular cancer?

Answer 1

Scrotal Ultrasound scan

Question 2

Tumor marker that may be raised in teratomas, but not in seminomas?

Answer 2

Alpha-fetoprotein

Question 3

Tumor marker that is raised both in teratomas and seminomas?

Answer 3

Beta-HCG

Question 4

Common metastasis sites for testicular cancer?

Answer 4

Lymphatics
Liver
Lungs
Brain

Question 5

What is the probability of remission of a Stage IV seminoma with lung-only metastases?

Answer 5

90%

Question 6

what is the adjuvant chemotherapy in stage I seminoma?

Answer 6

One cycle of carboplatin

Question 7

what is the adjuvant chemotherapy in stage II seminoma?

Answer 7

Three cycles of PEB (Cisplatin + Etoposide + Bleomycin)

Question 8

what is the adjuvant chemotherapy in stage IIC, III, IV seminoma?

Answer 8

3-4 cycles of PEB

Question 9

what is the adjuvant chemotherapy in stage IIC, III, IV seminoma?

Answer 9

3-4 cycles of PEB

Question 10

What is thte treatment for non-seminoma stage I patient with a high risk of relapse?

Answer 10

Retroperitoneal lymphadenoctomy OR two cycles of PEB

Question 11

treatment for skeletal metastasis in prostate cancer?

Answer 11

1. Biphosphonates
2. Denosumab
3. Alpharadin

Question 12

What is Gleason score?

Answer 12

evaluates the predominant histological aspect (primary degree) and the least representative aspect (secondary degree) of the neoplasm.