Prostate Cancer

Question 1

Define Prostate Cancer?

Answer 1

Primary malignant neoplasm of the prostate gland

Question 2

What are the risk factors for Pancreatic Cancer?

Answer 2

Age 
Afto-caribbean
Family History
Dietary Factors 
Occupational Exposure to cadmium

Question 3

What is the epidemiology of prostate cancer?

Answer 3

COMMON

2nd most common cause of male cancer deaths

Question 4

What are the presenting symptoms of Prostate Cancer?

Answer 4

Often asymptomatic
Lower Urinary Tract Obstruction
Metastatic Spread

Question 5

What symptoms would you see in associated of a Lower Urinary Tract Obstruction?

Answer 5

Increased Frequency of Urination
Hesitancy
Poor Stream
Terminal Dribbling 
Nocturia

Question 6

What symptoms are associated with metastatic spread?

Answer 6

Bone Pain
Cord Compression
Systemic Symptoms (malaise, anorexia, weight loss)
Paraneoplastic syndromes (e.g. hypercalcaemia)

Question 7

What are the signs of prostate cancer on physical examination?

Answer 7

Asymmetrical hard nodular prostate

Loss of midline sulcus

Question 8

What bloods would you do for Prostate Cancer?

Answer 8

FBC
U&Es 
PSA
Acid phosphatase
LFTs
Bone Profile

Question 9

What scans do we do for Prostate Cancer and why??

Answer 9

CT/MRI scan - Assesses extent of local invasion and lymph node involvement
Isotope Bone Scan - Check for bone metastases
Transrectal US and Needle Biopsy