Production and Action of hormones Flashcards

1
Q

What do hormones control

A

Development and growth
Metabolism of food items
Sexual function and reproductive gorwth and health
Cognitive function and mood
Maintenance of body temperature and thirst

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2
Q

Name 10 Primary endocrine organs

A
Pineal
Hypothalamus
Pituitary
Thyroid
Parathyroid
Thymus
Pancreas
Adrenal
Ovaries
Testes
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3
Q

Name 6 Secondary endocrine organs

A
Heart
Stomach
Liver
Kidneys
SKin
Small intestine
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4
Q

4 methods of local signalling

A

Gap Junctions
Contact-Dependant signals
Autocrine
Paracrine

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5
Q

Explain what is autocrine and paracrine signalling

A

Autocrine - target cell is the same cell that secreted signal

Paracrine - signal is secreted by one cell and diffuses to adjacent cells

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6
Q

What is another name for contact-dependant signals and what are they

A

Juxtacrine

Interaction between molecules on the surface membranes of cells

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7
Q

What is a neurohormone

A

Neurohormone is a hormone that is produced by neurosecretory cells and released by nerve impulses

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8
Q

Differences between neural and endocrine pathway

A

Neural is faster, has a single target cell, travels across synapse and each signal is identical in strength

Endocrine is much slower in comparison, it is exposed to all cells but only effects cells with receptors, travels in the blood and its intensity correlates to the amount of hormone secreted

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9
Q

What is an exocrine gland

A

A gland that secretes it’s products into ducts that lead to the target tissue

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10
Q

What endocrine glands secrete protein or peptide based hormones

Where are their receptors found

A

Ant. and Post. pituitary glands
Pancreas
Parathyroid

On the surface of the target cell

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11
Q

What glands secrete steroid hormones

Where are it’s receptors

A

Adrenal cortex, testes, ovaries and placenta

Intracellular

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12
Q

What glands secrete amino acid based hormones

Where are the receptors for these hormones found

A

thyriod and the adrenal medulla

Intracellular or extracellular

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13
Q

Characteristics of thyroid hormones

A

Derived from tyrosine
Lipophilic
bind to intracellular receptors

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14
Q

What are catecholamines

A

Neurohormones produced in the adrenal medulla and postganglionic fibres of the sympathetic NS

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15
Q

Tryptophan a precursor to

A

Serotonin
Melatonin
Vitamin B3

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16
Q

What are the four secondary messaging signals recognised in cells

A

Cyclic adenosine monophosphate (cAMP)
Cyclic guanosine monophosphate (cGMP)
Protein kinases (PKC)
Calcium and/or Phosphoinosities (IP3)

17
Q

What 3 factors affect target cell response

A

The levels of hormones in the blood
The relative number of hormone receptors on the target cell
The hormone-receptor affinity

18
Q

What are the main regulators of the endocrine system

A

Hypothalamus and pituitary gland