Physiology of Respiratory System Flashcards

1
Q

Where are central chemoreceptors located

A

Ventral surface of medulla

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2
Q

What is the function of central chemoreceptors

A

primarily sense pH changes in the central nervous system caused by alterations in arterial CO2
Chemoreceptors respond to reduced pH by sending sensory input to brain to stimulate hyperventilation

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3
Q

Where is the respiratory centre located

A

located in lower brain/upper brainstem

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4
Q

What does the medulla do

A

Sends signals to muscles
Ventral group stimulates expiratory movement
Dorsal group stimulates inspiratory movement

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5
Q

What does the Apneustic centre do

A

Sends signals for inspiration for long and deep breaths, controls intensity of breathing

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6
Q

Pneumotaxic centre function?

A

Inhibits inspiration to finely control respiratory rate

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7
Q

What are the three nerves involved in respiration and what do they do

A

Phrenic: stimulates diaphragm
Vagus: innervates diaphragm, larynx and pharynx
Posterior Thoracic nerve: stimulate intercoastal muscles around the pleura

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8
Q

What is the motor cortex responsible for

A

Responsible for initiating any voluntary muscular movement

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9
Q

Main functions of respiratory system

A

Exchange of O2 and CO2 between air and blood
Keeping body pH stable
Protection from harmful substances
Vocalisation

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10
Q

How does breathing occur

A

Volume of the thoracic cavity changes with the contraction and relaxation of muscles
The volume of lungs changes according to the thoracic cavity, which causes a change in the pressure of the lungs
Air diffuses from an area of high partial pressure to an area of low partial pressure

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11
Q

How does inspiration occur

A

air diffuses into lungs when atmospheric pressure is greater than intrapulmonary pressure

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12
Q

mechanism of inspiration

A

Diaphragm and intercostal muscles contracts
Thoracic cavity increases in size
Lung volume increases
Intrapulmonary pressure less than atmospheric pressure
Air diffuses from environment into the lung tissues via the bronchial tree, down the pressure gradient

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13
Q

HOW DOES EXPIRATION OCCUR

A

air to diffuse out of the lungs into the environment

intrapulmonary pressure > atmospheric pressure

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14
Q

mechanism for expiration

A

Diaphragm and intercostal muscle relaxes
Thoracic cavity decreases in size
Lung volume decreases
Intrapulmonary pressure > atmospheric pressure
Air (CO2) diffuses from the lung tissues into the environment down the pressure gradient

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15
Q

Muscles involved inactive inspiration

A
Scalenes
Sternocleidomastoid
Lasttissimus dorsi
Serratus anterior
Pectoralis minor
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16
Q

Muscles involved in active expiration

A

Abdominal wall muscles
Internal intercostal
Transversus thoracic

17
Q

What happens to intrapleural pressure during inspiration

A

Pleural cavity pressure becomes more negative as chest wall expands during inspiration

18
Q

What is tidal volume

A

Volume that enters and leaves the lungs during normal inspiration and expiration

19
Q

Inspiratory reserve volume

A

Extra volume that can be inspired from TV with maximal inspiration using accessory muscles

20
Q

Expiratory reserve volume

A

Extra volume that can be expired from TV with maximal expiration using accessory muscles

21
Q

What is Residual volume

A

Volume that remains despite maximum expiration

22
Q

What is Vital capacity

A

Maximum volume that can be exhaled after a maximum inspiration

IRV + TV + ERV

23
Q

What is Inspiratory capacity

A

Total volume breathed in from expiration to maximum inspiration

24
Q

How to calculate total lung capacity

A

IRV + TV + ERV + RV