Problems in early pregnancy Flashcards

1
Q

What is hyperemesis gravidarum?

A

Such bad N+V that the women cannot maintain adequate hydration
Fluid, electrolyte + nutritional status are endangered

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2
Q

Peak onset of hyperemesis gravidarum

A

6-11 weeks

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3
Q

Signs of hyperemesis gravidarum

A

Dehydration
+++ ketones in urine
Liver tenderness

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4
Q

In suspected hyperemesis gravidarum: what needs to be ruled out?

A

Other cause of vomiting (e.g. UTI, thyrotoxicosis)

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5
Q

hyperemesis gravidarum: when to admit

A

Admit if cannot tolerate oral fluids

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6
Q

Tests in hyperemesis gravidarum

A

LFT + electrolytes

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7
Q

Mx of more severe hyperemesis gravidarum

A

IV rehydration + antiemetics

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8
Q

In hyperemesis gravidarum which anti-emetics are most effective?

A

Antihistamines (promethazine or cyclizine)

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9
Q

If hyperemesis gravidarum is prolonged, what is required?

A

B vitamin supplementation

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10
Q

Miscarriage: definition

A

Loss of pregnancy before viability (24 weeks)

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11
Q

Recurrent Miscarriage: definition

A

Loss of >3 consecutive pregnancies with the same partner

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12
Q

Features of miscarriage (3)

A

PV bleeding
Abdo pain
Regression of pregnancy symptoms

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13
Q

Foetal abnormality is the most common cause of Miscarriage. Give some examples

A

Sporadic chromosmal abnormalities (most common)
Structural (NTD)
1 in 3 Down’s syndrome pregnancies miscarry

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14
Q

What type of miscarriage?
Bleeding + pain, but pregnancy continues. Cervical os is closed, uterine size is correct for dates. No long-term harm to the baby

A

Threatened

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15
Q

Type of Miscarriage:

Vaginal bleeding + cervical os is open

A

Inevitable (presents in the process of miscarriage + nothing can be dome to save it)

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16
Q

Type of Miscarriage:

History of pain + bleeding, noew subsided. Cervical os is closed

17
Q

Type of Miscarriage:

Bleeding, cervical os open, scan shows some debris in the uterus

A

Incomplete

not all the products of conception have been expelled from the uterus

18
Q

Type of Miscarriage:

Seen on a routine scan, entire gestation sac is in the uterus, but no foetal heart beat

19
Q

Pregnancy test will remain positive for XXX after the end of a miscarriage

20
Q

What type of USS should be used to assess the viability of a pregnancy?

A

Transvaginal USS

21
Q

USS findings suggestive of ectopic pregnancy

A

No intra-uterine pregnancy
Free peritoneal fluid
Thickened endometrium
Adnexal mass

22
Q

What is used for medical Mx of miscarriage?

MOA

A

MISOPROSTOL

Induces contractions to expel uterine contents

23
Q

How long after complete miscarriage should women do a pregnancy test?

A

3 weeks (return to hospital if +VE)

24
Q

What are the 2 surgical options for miscarriage?

A

Manual vacuum aspiration (under local)

OR surgical evacuation under GA

25
Complications oc Miscarriage surgical Mx
Intrauterine infection, trauma to cervix, haemorrhage, retained products
26
Predisposing factors to ectopic pregnancy
PID Tubal surgery IUD
27
Initial investigation in suspected ectopic
PT (will be +ve)
28
Scan in suspected ectopic
Transvaginal USS
29
Gold standard for diagnosis of ectopic | When should this be done?
Laparoscopy | If diagnosis is uncertain
30
Difference in hCG between ectopic + miscarriage + early pregnancy
Ectopic: Slowly rise + plataeu Miscarriage: fall rapidly Early preg: rise rapidly
31
Signs (o/e) in ectopic
Tenderness (rebound?) Cervical excitation Unilateral adnexal tenderness
32
Only situation for expectant mx of ectopic
Few symptoms + clinically stable
33
When is medical management of ectopic offered?
If woman can return to follow-up hCG <5000 Not in severe pain
34
Medical Mx of ectopic Drug Downsides
Methotrexate IM May require 2nd dose Can take 6 weeks for hCG to return to normal
35
When are medical and surgical management offered in ectopic? (hCG levels)
hCG 1500-5000
36
When is ONLY surgical recommended for ectopic?
Mass >35mm PAIN!! hCG >5000 Foetal heart beat visible
37
Peak time for ectopics to present
6-8 weeks