Principles of Forebrain and Brainstem Disease Flashcards
What is the mesencephalon?
Midbrain
What is the metencephalon?
Pons
What is the myeloencephalon?
Medulla oblongata
What is the rhomboencephalon?
Pons (metencephalon) and medulla oblongata (myeloencephalon)
Name the cranial nerves located in
- Midbrain
- Pons
- Medulla oblongata
- Occulomotor (III) and trochlear (IV)
- Trigeminal (V)
- Rest (except 1+2)
What are the roles of the olfactory bulbs/tracts?
Perception of smell Limbic system (instinct/mood)
Which CN are associated with the olfactory bulbs/tracts?
Olfactory (CNI)
Outline the pathway of the olfactory nerve…
Cell bodies in the nasal epithelium –> Cribriform plate of the ethmoid bone –> Olfactory bulbs –> Olfactory tracts
What are the roles of the temporal lobes of the telencephalon?
Auditory area
Vestibular conscious perception
What are the roles of the frontal lobes of the telencephalon?
Motor - corticospinal and corticonuclear tracts
What are the roles of the parietal lobes of the telencephalon?
Sensory-motor
What are the roles of the occipital lobes of the telencephalon?
Visual conscious perception
What proportion of the optic nerve fibres crossover in the optic chiasm in horses, dogs and cats?
Horse - 85%
Dog - 75%
Cat - 66%
What is the significance of the proportion of optic nerve fibres that crossover in the optic chiasm in different species?
An animal with fewer fibres crossing over e.g. human will show a much less prominent indirect PLR. This should be taken into account as a reduced PLR cannot always be assumed to be a lesion.
Outline the neural pathway of vision…
Retina –> optic nerve –> optic chiasm –> optic tract –> lateral geniculate nucleus –> optic radiation –> occipital lobe
How does the optic nerve differ from the other CN?
It is an extension of the CNS
Myelinated
Has retinal ganglion cells, glial cells and meninges
How can an animal’s vision be assessed?
Dim vs bright light Observing the animal moving in an unfamiliar env Negotiating an obstacle course Visual placing Menace response
Outline the efferent neural pathway in the menace response…
Occipital lobe –> Associated fibres –> Motor cortex –> Projection fibres –> Pontine nucleus –> Transverse fibres of the pons –> Cerebellar cortex –> Efferent cerebellar fibres –> Facial nuclei –> Facial nerve –> Obicularis oculi muscle
Which muscle is responsible for closing the eyelid?
Obicularis oculi muscle
When can the menace response be absent without any pathology?
<10-12w old SA (haven’t learned it yet)
Stressed patients
Lethargic patients
Disorientated patients
What effects can forebrain dysfunction have on mental status?
Altered –> depression, delirium, confusion, stupor, coma
Behavioural changes e.g. hemi-neglect syndrome
Seizures
What is hemi-neglect syndrome?
One hemisphere of the brain is damaged which causes a deficit in attention to and awareness of one side of space e.g. only eating from one half of a food bowl
How can gait be affected by forebrain dysfunction?
No change
Head pressing, pacing, circling
Proprioceptive ataxia and tetraparesis
How can posture be affected by forebrain dysfunction?
Head turn (+body turn, circling) towards side of lesion
Are postural reaction deficits lateral or contralateral?
Contralateral
What are the 3 branches of the trigeminal nerve?
Ophthalmic
Maxillary
Mandibular