Principles of evolution, genetics and behavioural development Flashcards

1
Q

Why is studying evolution and genetics important

A

Have to understand how we have been shaped by evolution in order to understand how we behave now

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2
Q

who wrote the origin of species

A

Darwin

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3
Q

what two problems did the origin of species solve

A

the problem of history
the problem of design

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4
Q

what is the problem of history

A

Animals are structured in ways that look like variations on a theme
Darwin realised that for animals to be related they share a common ancestor

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5
Q

what is the problem of design

A

○ Organisms everywhere seem to be well adapted for their surroundings e.g. fennec vs artic fox
-presumed this must be designed deliberately
Explained by Darwin - useful features retained and useless ones disappear

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6
Q

what assumptions did Darwin make

A

Variation in a population
Heredity – variation can be passed on to offspring
Competition - not all individuals reproduce to the same extent

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7
Q

What does natural selection do

A

Leads to successive changes over generations

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8
Q

what are homologies

A

similarities between organisms due to common ancestry

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9
Q

what are analogies

A

similarities due to parallel selective pressures

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10
Q

what is the modern synthesis

A

Fisher and Wright combined natural selection (Darwin) with genetics (Mendel) to create our understanding of evolutionary theory (1930s)

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11
Q

explain evidence for evolution in Finch’s

A
  • Drought led to changes in seeds in habitat to large and hard
  • Finches with larger beaks more likely to survive and reproduce
    Offspring receive genes for larger beak and frequency increased dramatically over 2 years
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12
Q

what disproves the “gaps in the record”

A
  • Fossilisation is hit or miss and depends on conditions - fossils are a bonus
    Evidence of full lineage of whale that supports evolution
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13
Q

evidence against “too complex to have arisen by chance”

A
  • Mutation is a chance process
  • Natural selection is not
    Non-random and benefits individuals
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14
Q

what is a phenotype

A

physical attributions
Genotype and its interaction with the environment

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15
Q

where do we see variation

A

in continuous measures e.g. height

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16
Q

what does DNA stand for

A

Deoxyribonucleic acid

17
Q

explain the structure of DNA

A

two strands, with principle of base pairing. (A-T C-G)
Organised into pairs of chromosomes (diploid organism) -
23 pairs

18
Q

what are genes

A

Sequence of DNA bases - code for a specific protein

19
Q

what is an allele

A

An allele is an alternate form of a gene - codes for a different form of a protein

20
Q

what is transcription

A
  • A copy of one strand created - forms mRNA
    mRNA leaves nucleus and bind to ribosome
21
Q

what is translation

A
  • Ribosome translate the code from RNA into amino acids
    • Chain of amino acids form proteins
      U instead of T in mRNA
22
Q

how many amino acids are there

23
Q

how many bases code for an amino acid

A

3 - known as codon

24
Q

what is redundant coding

A

more than one codon codes for same amino acid

25
what are stop codons
stop translation
26
how many base pairs in the human genome
3.2 billion base pairs
27
how much approx of DNA are introns
60%
28
what is an intron
non coding sequence of DNA
29
What are non coding sequences of DNA
- May be parasitic - Transposable elements - Simple sequence repeats - used for genetic fingerprinting Regulatory functions
30
what is mitosis
- Part of the cell cycle in which replicated chromosomes are separated into two new nuclei. produces genetically identical cell
31
what is meiosis
produces gametes recombines two parental genomes
32
how does genetic mutation occur
-Single-base substitutions -Simple sequence repeat expansions and contractions -Transposable element insertions -Segmental changes (e.g. extra chromosomes)
33
why do most mutations not have a phenotypic effect
Lots of redundancy in the genetic code Lots of biological systems are also redundant
34
why do most mutations that do have an effect cause damage
A complex system – more ways to make it worse than to make it better
35
what are mendelian diseases and example
caused by double recessive alleles - so stay present but at low frequencies e.g. cystic fibrosis
36
what is an association study
Assemble large groups of individuals with and without the trait and compare the frequency of different alleles
37
what is a linkage study
Look at who is affected and who is unaffected within a large family, and trace which sections of which chromosomes are shared