Primary Sclerosis Cholangitis

Question 1

What is primary sclerosing cholangitis?

Answer 1

Chronic cholestatic liver disease of unknown cause, in which inflammation and fibrosis narrow and eventually obstruct intrahepatic and extrahepatic bile ducts

Question 2

Cause of primary sclerosing cholangitis? Associated conditions?

Answer 2

Unknown; 2/3 of patients have ulcerative colitis

Question 3

Findings Dx of primary sclerosing cholangitis on contrast radiography?

Answer 3

Characteristic beaded appearance of the intrahepatic biliary tree

Question 4

What is a severe complication of primary sclerosis cholangitis?

Answer 4

Cholangiocarcinoma