Primary Sclerosing Cholangitis Flashcards
1
Q
whats it characterised by?
A
progressive obliterating fibrosis of intra- and extra hepatic ducts
eventually leading to cirrhosis
2
Q
associations
A
ulcerative colitis
3
Q
diagnosis
A
usually by MRCP or LFT
most commonly after routine blood testing in IBD patient
increased alkaline phosphatase
then increased bilirubin
4
Q
symptomatic presentation
A
itching, pain, rigours, or jaundice
5
Q
Mx
A
Mx of CLD
transplantation
ursodeoxycholic acid
ERCP of extra hepatic strictures
6
Q
how is it related to AIDS?
A
Sclerosing cholangitis secondary to cryptosporidium infection seen in pts with AIDS
