Gastritis

Question 1

Gastropathy

Answer 1

injury to the gastric mucosa associated with epithelial cell damage + regeneration

little or no accompanying inflammation

Question 2

Gastritis

Answer 2

inflammation of the gastric mucosa

Question 3

How does use of aspirin or NSAIDs –> mucosal damage

Answer 3

they deplete mucosal prostaglandins by inhibiting the cyclo-oxygenase pathway

Question 4

Treatment for gastropathy

Answer 4

PPI with removal of the offending cause if possible

Question 5

Most common cause of gastritis?

Answer 5

H. pylori infection

others: AI gastritis, viruses + duodenogastric reflux

Question 6

Diagnosis of gastritis?

Answer 6

histologically, incidental finding from endoscopy biopsy

Question 7

Acute inflammation (in gastritis)

Answer 7

associated with neutrophilic infiltration

Question 8

Chronic inflammation (in gastritis)

Answer 8

characterised by mononuclear cells

mainly lymphocytes, plasma cells and macrophages

Question 9

Tx gastritis

Answer 9

no specific treatment, although eradication treatment for H. pylori is given