primary (congenital) and secondary (acquired) immune deficiences

Question 1

primary

Answer 1

genetically determined (genetic defect, single gene)

Question 2

primary is divided into 5 groups: B lymphocyte deficiencies

Answer 2

(defects in antibody production)

Question 3

primary is divided into 5 groups: T lymphocyte deficiencies

Answer 3

(defect in development and function of cell-mediateed immunity)

Question 4

primary is divided into 5 groups: combined deficiencies

Answer 4

(directly affect the developmet of B and T lymphocytes)

Question 5

primary is divided into 5 groups: complement deficiencies

Answer 5

(inability to clear circulating immune complexes)

Question 6

primary is divided into 5 groups: phagocytic deficiencies

Answer 6

(recurrent infections with the same group of microorganisms associated with antibody and complement deficiencies)

Question 7

secondary

Answer 7

• causes by cancer
• can result from loss of serum proteins through the kidneys in nephrotic syndrome, through skin in severe burns or dermatitis or through the GI tract in enteropathy
• More common, not related to genetic defects