pathophysiology, mechanims, and clinical manifestations of Type I, Type II, Type III, and Type IV Hypersensitivity Reactions.

Question 1

type 1 - most common allergic reactions

Answer 1

-environmental reactions
-IgE antibody
S/S - seasonal allergies

Question 2

type 2 - tissue specific reactions

Answer 2

reactions against specific tissues. IgG and IgM antibodies

S/S - autoimmune disease and graves disease

Question 3

type 3 - immune complex reactions

Answer 3

Reactions against antigen in blood/body fluids

-S/S - lupus

Question 4

cell-mediated reactions

Answer 4

• Mediated by T lymphocytes, specific cells
• Doesn’t involve any type of antibody
• S/S - graft rejection, skin test for TB, skin allergic reactions for poison ivy and some metals