Primary Ciliary Dyskinesia

Question 1

How is PCD inherited?

Answer 1

Autosomal recessive

Question 2

What is the difference between PCD and Kartagener’s syndrome?

Answer 2

PCD = cilia lining the repiratory tract, fallopian tube and sperm function inefficiently or in an unsynchronized fashion.

Kartagener’s syndrome - is a triad of:

1. Situs Invertus
2. PCD
3. Abnormal sinuses causing sinusitis & bronchiectasis

Question 3

What % of PCD also have situs inversus?

Answer 3

50%

Question 4

What are some clinical features of PCD?

Answer 4

• Recurrent respiratory infections
• Otitis media
• Sinusitis
• Infertility