Primary and Secondary Lesions Flashcards
Vesicle > 1 cm
Bulla
Blisters, pemphigus vulgaris
Bulla
Palpable. Elevated, circumscribed, encapsulated lesion in dermis or subcutaneous layer
Cyst
Flat, circumscribed lesion changed from normal color of skin.
Macule
Freckles, nevi (small moles)
Macule
Elevated, firm “marble-like” circumscribed lesion deeper in dermis than a papule
1-2cm
Nodule
Erythema nodosum, fungal infection, lipoma, neoplasms, sarcoidosis, tuberculosis
Nodule
Elevated, firm circumscribed area
Papule
Lichen planus, mastocytoma, wart
Papule
Flat, non-palpable irregulary shaped macule >1cm
Patch
Cafe-au-lait patch, mongolian spots, port-wine stains, vitiligo
patch
Cafe-au-lait patch is also known as
birthmark
Red, purple, nonblanching discoloration
Less than 0.5cm
Greater than 0.5cm
Petechiae or purpura
Petechiae
Purpura
Caused by RBCs leaking out of capillaries. Trauma is most common cause
Petechiae and purpura
Directly associated with disease process
Primary lesions
Differential for ecchymoses must always include
physical abuse
DIC, Henoch-Schonlein purpura, RMSF, and thrombocytopenia
Petechiae and purpura
Elevated, firm and rough lesion with flat top surface > 1 cm
Plaque
Actinic keratosis, psoriasis, and seborrheic keratosis
plaque
Elevated, superficial lesion similar to a vesicle but with purulent fluid (pus)
Pustule
Acne, folliculitis, impetigo
Pustule
Fine, irregular red lines due to capillary dilatation
telangiectasia
Acne rosacea
telangiectasia
Elevated, solid lesion deep in dermis >2cm
tumor
Benign tumors, neoplasms
tumor
Elevated, circumscribed superficial lesion filled with serous fluid
Vesicle
Blister, contact dermatitis, herpes simplex virus, varicella chickenpox, shingles herpes zoster
vesicle
Transient
Wheal (hive,urticaria)
Involves deeper dermis and hypodermis (subcutaneous) tissue. Associated with ACE inhibitors such as lisinopril
Angioedema
Mast cell degranulation in superficial dermis with resulting vascular permeability. Pruritic from histamine release
Wheal (hive, urticaria)
Pruritic
Itchy
Wheal (hive, urticaria) will or will not blanch?
Blanch
Allergic reactions, insect bites, urticaria cause
wheals (hive, urticaria)
Primary skin lesions with modifications
Secondary skin lesions
Thinning of skin surfaces and loss of skin markings
Atrophy
Thin appearing, wrinkled surface
Epidermal atrophy
Results in a detectable depression
Dermal atrophy
Aged skin, striae
Atrophy
Dried serum, blood, or purulent exudates
crust
Results from ruptured vesicles, pustules, or bullae. Usually multicolored
Crust
Atopic dermatitis, contact dermatitis, impetigo, scabs
crust
Loss of part of epidermis with glistening, depressed moist appearance. Incomplete loss of dermis
Erosion
Ruptured vesicle or bulla
Erosion
Loss of epidermis leaving a linear, hollowed-out crusted area
Excoriation (scratch)
Abrasions, scabies, scratches
Excoriation (scratch)
Linear crack from epidermis to dermis
fissure
angular cheilitis, funal infection (tinea pedis)
Fissure
Dermal thickening associated with inflammation. Loss of elasticity and pliability
Induration
Red, inflamed, thickened, and tender
induration
Cellulitis, neoplasm, scleroderma
induration
Irregular, elevated progressively enlarging scar growing beyond wound boundaries. Often following surgery
Keloid
Excessive collagen formation during healing
Keloid
Common in African Americans
Keloid
Rough, thickened epidermis due to persistent rubbing, itching, or skin irritation.
Lichenification
Visible and palpable skin thickening with accentuated skin lines
Lichenification
Lichenification usually involves __________ surfaces
flexor
Chronic dermatitis
lichenification
Heaped up, kearatinized cells from corneum manifesting as flaky skin due to imperfect cornification
Scale
Can be dry or oily
Normally silver/white or tan
Scale
Actinic keratosis, eczema, psoriasis, seborrheic dermatitis
scale
Fibrous tissue that replaces normal skin following injury to dermis
scar
Loss of epidermis and dermis, typically concave
ulcer
Reveals hypodermis (subcutaenous tissue)
Blue or reddish
Ulcer
May include fibrotic tissue or eschar formation
Ulcer