Acute Inflammatory Dermatoses

Question 1

Lesions develop and disappear within hours, but episodes may last for days to weeks.
Trunks, extremities, ears

Answer 1

Urticaria (hives)

Question 2

Antigen induced, mast cell degranulation through IgE abs

Follows exposure to various antigens - pollens, foods, drugs, insect venom

Answer 2

Urticaria (hives)

Question 3

Subtle histological changes.
Superficial dermal perivenular infiltrate > neutrophils > mononuclear cells
Collagen bundles widely spaced due to dermal edema
Dilated lymphatics from absorption of edema fluid
No epidermal changes

Answer 3

Urticaria (Hives)

Question 4

Includes contact dermitis and atopic dermatitis (eczema)

Answer 4

Acute eczematous dermatitis (spongiotic dermatitis)

Question 5

Inflammatory rx caused by exogenous chemical

Irritant and allergic forms

Answer 5

Contact dermatitis

Question 6

Produced by substance that has direct toxic effect on skin
Ex. Acids, detergents, alkalis, frequent hand washing

Not an immunological condition.
Rash begins shortly after exposure

Answer 6

Irritant

Question 7

Cell mediated, delayed type hypersensitivity rx (type 4)

Answer 7

Allergic

Question 8

Antigen on skin taken up by Langerhan’s Cells > migrate via dermal lymphatics to LNs > Present antigen to CD4 Thelper cells > effector and memory cells

Answer 8

Allergic

Question 9

Sensitization of skin 1-2 wks after first exposure to allergen.
Re-exposure causes dermatitis in hours-days

Answer 9

Allergic

Question 10

Common allergens - poison ivy, mangos, iodine, nickel, rubber, cosmetics

Answer 10

Allergic

Question 11

Produce urushiol as common allergenic substance

Answer 11

Allergic

Question 12

Fluid in vesicles do/do not contain an allergen and can/cannot induce a disease in others for allergic contact dermatitis?

Answer 12

Do not

Cannot

Question 13

Erythematous papules and vesicles with oozing > crusting and scaling
Very pruritic

Answer 13

Allergic

Question 14

Chronic, waxing and waning, extremely pruritic condition beginning in first year of life
Family history of allergies, asthma, and eczema
Worse in winter due to decreased humidity
Etiology unknown

Answer 14

Atopic dermatitis (eczema)

Question 15

Papules, vesicles, oozing, and crusting
Babies - face, diaper area, and extensor surface of extremities
Children and adults - neck, face, axillae, antecubital, and popliteal fossa

Answer 15

Atopic dermatitis (eczema)

Question 16

Atopic dermatitis also known as

Answer 16

eczema

Question 17

Skin very dry
Itching > scratching > itching

Chronically can lead to lichenification - epidermal thickening

Answer 17

Eczema

Question 18

Coin shaped.
Itchy red plaque with vesicles and distinct borders
Young adults.
Same treatment as for eczema

Answer 18

Nummular dermatitis

Question 19

Winter itch.
Older people in winter.
Dry, cracked skin becomes itchy

Answer 19

Asteatotic dermatitis

Question 20

Avoid excessive bathing, use room humidifiers, moisturizers, topical steroids if inflamed

Answer 20

Asteatotic dermatitis

Question 21

Spongiosis (intercellular edema)

Exocytosis of lymphocytes

Answer 21

Acute eczematous dermatitis

Question 22

Intercellular edema also known as

Answer 22

Spongiosis

Question 23

From mast cell degranulation causing microvascular hyperpermeability

Answer 23

Wheals

Urticaria (hives)