Prevention & Remission of T2DM

Question 1

what are the 2 different approaches to preventing disease

Answer 1

change something in the whole population

OR target those at high risk and give preventative intervention

Question 2

what is the pre-diabetes level of fasting glucose level

Answer 2

6-7mmol/L

Question 3

what is the main risk factor for developing T2DM

Answer 3

obesity

Question 4

what lifestyle changes can be made to reduce risk of diabetes

Answer 4

low calorie diet, increased exercise, therefore weight loss associated with these is the important change

Question 5

describe the problem in lower income patients and prevention of diabetes

Answer 5

highest risk of developing but also poorest engagement in current prevention programmes

Question 6

how are people at high risk of diabetes identified

Answer 6

screening for impaired glucose tolerance(HbA1c), as well as other risk factors(eg genetics)

Question 7

describe what remission means

Answer 7

when signs and symptoms of a disease are reduced, can be partial or complete
a period of time when a disease is less severe or not affecting someone

Question 8

describe how T2DM remission can be achieved

Answer 8

by reversing hyperglycaemia

Question 9

what different steps are taken in order to try and achieve remission of T2DM

Answer 9

very low calorie diet for many weeks, with slow increase of calories after, weight loss maintenance for up to 1yr and relapse management

Question 10

what can remission of T2DM be defined as

Answer 10

by being able to keep HbA1c below 6.5%(48mmol/mol) without need of any T2DM medication

Question 11

is T2DM reversible for all patients

Answer 11

complete remission has only been shown to be possible for some patients