Diabetes Complications: Neuropathy Flashcards

1
Q

what types of neuropathy are seen in diabetes

A

peripheral, proximal(rare), autonomic, focal neuropathy

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2
Q

what is the most common type of neuropathy seen in diabetes

A

peripheral

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3
Q

describe peripheral neuropathy

A

pain/loss of feeling in feet and hands

‘glove and stocking neuropathy’

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4
Q

describe proximal neuropathy

A

pain in thighs, hip, buttocks leading to weakness in legs

usually one sided and self-limiting

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5
Q

describe autonomic neuropathy

A

affect autonomic nerve system; changes in bowel, bladder function, sexual response, sweating, heart rate, blood pressure

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6
Q

describe focal neuropathy

A

sudden weakness in one nerve or a group of nerves causing muscle weakness or pain
(eg carpal tunnel)

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7
Q

what are some of the risk factors for neuropathy

A

increased length of diabetes, poor glycaemic controls, T1DM>T2DM, high cholesterol/lipids, smoking, alcohol, genes

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8
Q

what are the symptoms associated with peripheral neuropathy

A

numbness/insensitivity, tingling/burning, sharp pain/cramps, sensitivity to touch, loss of balance/coordination

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9
Q

what are some of the consequences of peripheral neuropathy

A

painless trauma, foot ulcer, Charcot foot, peripheral vascular disease

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10
Q

what are the features of the ‘diabetic foot’

A

neuropathic ulcer, proximal arterial occlusion, digital gangrene, Charcot’s foot, clawing of toes

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11
Q

what is Charcot arthropathy

A

destructive inflammatory process, fractures/bony destruction and deformity of the foot
(lasts around 3 months, 8 months recovery)

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12
Q

what is the presentation of Charcot arthropathy

A

present as hot swollen foot in someone with neuropathy

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13
Q

what treatment is used for Charcot

A

non-weight bearing; total contact cast or air boost

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14
Q

what features are seen as being at high risk of diabetic foot complications

A

sensation impaired + foot pulses absent and/or if skin callus or foot deformity

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15
Q

what are some of the drugs that can be used to treat painful neuropathy

A

amitriptyline, gabapentin

don’t always work very well and can cause more issues with side effects

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16
Q

what is one of the main autonomic neuropathies seen in diabetes

A

gastroparesis; slow stomach emptying, persistent nausea + vomiting, bloating, loss of appetite, can effect BG levels

17
Q

what treatments are used for gastroparesis

A

improved glycaemic control, promotility drugs(eg domperidone), anti-nausea, pain killer if abdo pain, gastric pacemaker

18
Q

what effect can autonomic neuropathy on sweat glands

A

can prevent them from working properly, body can’t regulate temp/ as it should, can cause profuse sweating at night or while eating

19
Q

what effects can autonomic neuropathy have on the cardiovascular system of diabetes patients

A

BP; may drop sharply after sitting or standing, causing faint/light-headedness
HR; may stay high instead of rising and falling with normal activity