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Pharmaco > Pressure Ulcer > Flashcards

Pressure Ulcer Flashcards

1
Q

What are the medications for pressure/decubitus ulcer

A

Pipericillin-tazobactam, Ciprofloxacin, Clindamycin, Vancomycin

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2
Q

What is the class of Pipericillin-Tazobactam

A

Beta lactam with oxapenam, aminopenicillin

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3
Q

What is the class of ciprofloxacin

A

2nd gen fluoroquinolone

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4
Q

What is the class of clindamycin

A

Lincosamide protein synthesis inhibitor

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5
Q

What is the class of vancomycin

A

Non beta lactam, glycopeptide

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6
Q

MOA of Pipericillin-Tazobactam

A

Inhibit bacteria cell wall synthesis (inhibit transpeptidation)

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7
Q

MOA of ciprofloxacin

A

DNA synthesis inhibitor

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8
Q

MOA of clindamycin

A

Protein synthesis inhibitor

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9
Q

MOA of vancomycin

A

Inhibit bacteria cell wall (inhibit transglycosylation)

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10
Q

Why is clindamycin used

A

Broad spectrum (gram positive, negative and anaerobic bacteria when less toxic alternatives are not effective)

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11
Q

When is vancomycin used

A

In dividing gram positive bacteria
Reserved for serious infection like MRSA

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12
Q

AE of Pipericillin-Tazobactam

A

Rash, diarrhoea, thrombophlebitis

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13
Q

AE of ciprofloxacin

A

Nausea, vomiting, headache, restless, diarrhoea, pain & inflammation at site of injection, anaphylaxis, photosensitivity, seizure, tendon rupture, superinfection, peripheral neuropathy, hepatotoxicity, pseudomembranous colitis

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14
Q

AE of clindamycin

A

Nausea, diarrhoea, vomiting, headache, constipation, anaphylaxis, superinfection, myopathy, pseudomembranous colitis

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15
Q

AE of vancomycin

A

Nausea, vomiting, anaphylaxis, superinfection, nephrotoxicity, ototoxicity, red man’s syndrome

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16
Q

What medications can be used to treat MRSA

A

Vancomycin, clindamycin, sulfoamide

17
Q

How to treat MRSA at home

A

7-10d of trimethoprim-sulfamethoxazole (Bactrim), clindamycin, minocycline, doxycycline and linezoid
(*must take med on time and finish entire course)
If no effective, need to give diff abx/go hosp

18
Q

How to treat MRSA in hospital

A

IV abx until improvement

19
Q

How to treat MRSA on discharge

A

IV/PO abx for a short period to 6-8wks
IV needs to be given by visiting nurse
If MRSA colonised and not infected, give mupucin ointment and chlorhexidine soap

20
Q

Who should not take ciprofloxacin

A

Elderly with tendonitis or athlete with tendon rupture

Pharmaco (11 decks)

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