Cellulitis Flashcards

1
Q

What are the medications for cellulitis

A

Cephalexin & clindamycin

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2
Q

Class of Cephalexin

A

Beta lactam (1st gen cephalosporin)

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3
Q

Class of Clindamycin

A

Lincosamide protein synthesis inhibitor

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4
Q

MOA of Cephalexin

A

Inhibit bacteria cell wall synthesis

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5
Q

MOA of Clindamycin

A

Protein synthesis inhibitors

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6
Q

Why is Cephalexin used

A

Broad spectrum (good coverage of gram +ve & -ve bacteria)

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7
Q

Why is clindamycin used

A

Broad spectrum (gram +ve, -ve, anaerobic when less toxic alternatives are not effective)
Good for MRSA

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8
Q

AE of Cephalexin

A

Rash, diarrhoea, thrombophlebitis

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9
Q

AE of clindamycin

A

Nausea, diarrhoea, constipation, headache, vomiting, anaphylaxis, superinfection, myopathy, pseudomembranous colitis

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