Preservatives Flashcards
prevent microbial contamination, maintain sterility in the event of accidental contamination
PRESERVATIVES
Effective at low concentrations against all possible microbes, nontoxic, compatible, stable for the shelf life
PRESERVATIVES
(p-hydroxybenzoic acid)
PARABENS
Useful for liquid dosage forms, Antifungal, Preservative effect tends to increase with molecular weight
PARABENS
antifungal preservative; preserve preparations containing sugars
Sorbic Acid
more effective against yeast, more oil soluble so it is preferred for oils and fats
Propylparaben
occurs primarily in rose oil and pine needle oil; used in perfumery
Phenylethyl Alcohol
preservative in acidic liquid preparations in which benzoic acid is released
Sodium Benzoate
bacteriostatic in pharmaceuticals for injection, opthalmic, and intranasal
Chlorobutanol
more effective against molds
Methylparaben
antifungal preservative
Sodium Propionate
common in vials of injectables with 1%to 4% concentrations in water or saline
Benzyl Alcohol
preservatives in foods and pharmaceuticals at low pH
Benzoic Acid