Anthelminthics Flashcards

1
Q

Drugs under Nematodes

A

Albendazole, Mebendazole (Antiox ®), Pyrantel Pamoate, Piperazine, Ivermectin, Thiabendazole, Diethylcarbamazine

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2
Q

Drugs under Trematodes

A

Praziquantel

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3
Q

Drugs under Cestodes

A

Niclosamide

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4
Q

Inhibits microtubule synthesis

A

Albendazole

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5
Q

Inhibits microtubule synthesis, Depletes glucose

A

Mebendazole (Antiox ®)

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6
Q

Depolarizing neuromuscular agent (nicotinic receptors)

A

Pyrantel Pamoate

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7
Q

Flaccid paralysis of helminth (Blocks Ach response)

A

Piperazine

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8
Q

Targets GABA receptors—> paralysis

A

Ivermectin

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9
Q

Also affects microtubular aggregation

A

Thiabendazole

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10
Q

Increases membrane permeability to calcium—>

contraction—>vacuolization—>parasite death

A

Praziquantel

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11
Q

inhibits oxidative phosphorylation

A

Niclosamide

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12
Q

Adverse effects of Thiabendazole

A

Erythema multiforme and SJS (fatal)

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13
Q

Albendazole, Mebendazole (Antiox ®), Pyrantel Pamoate, Piperazine, Ivermectin, Thiabendazole, Diethylcarbamazine

A

Roundworm (intestinal and muscle), Hookworms (old and new), Whipworm, Pinworm

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14
Q

Onchocerca volvulus (river blindness)

A

Ivermectin

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15
Q

Strongyloidiasis (threadworm)

A

Thiabendazole

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16
Q

Filariasis

A

Diethylcarbamazine

17
Q

For intestinal cestodes only: T. saginata, D latum, H. nana

A

Niclosamide