Presentation of kidney disease Flashcards
what are the possible features of kidney disease presentation
asymptomatic loin pain/ urinary symptoms haematuria (microscopicm painless macroscopic haematuria) proteinuria hypertension AKI CKD nephrotic syndrome nephritic syndrome
what do the majority of people with kidney disease present with
are asymptomatic- will be an incidental finding
what causes systemic symptoms in kidney disease
underlying disease (DM, CTD, vascular disease) or effects of loss of kidney function (uraemic, fluid retention, bone pain)
what happens when the kidney stops excreting urea
uraemia
what are the can be caused by uraemia
pericarditis, encephalopathy, neuropathy, asterixis, gastritis
what happens when the kidney stops maintaing fluid balance
fluid retention- oedema, ascites
what happens when the kidney stops maintaining electrolyte balance
hyperkalaemia- arrhythmia
what happens when the kidney stops maintaining acid- base balance
metabolic acidosis
kussmauls respiration
what happens when the kidney stops metabolising Vit d and excreting phosphate
renal bone disease (bony pain) and vascular calcification
what happens when the kidney stops producing erytropoietin
anaemia
what happens when the kidney stops excreting drugs
can get drug toxicity - digoxin, gabapentin
what happens when the kidney stops working as a barrier to loss of proteins
proteinuria and nephrotic syndrome
how might asymptomatic patient’s get diagnosed with kidney disease
dipstix (microscopic haematuria &/or protein uria) reduced eGFR on biochem screen raised BP abdo imaging screening because of family history
what local/ renal signs and symptoms might patients present with
loin/ abdo pain macroscopic haematuria UTI arterial bruits palpable kidneys
what questions should you ask in the systemic enquiry
appetite & weight loss nausea & vomiting dyspepsia dyspnoea urinary symptoms e.g. frequency, urgency, hesitancy, polyuria & nocturia joint pains & arthralgia skin rashes