Presentation 5: Skeletal System Flashcards
Connective Tissue
cartilage, bone, and adipose
all have extracellular fibers + proteins
provide support for organs and movement
Extracellular fibers (proteins)
Collagen (found in skin), Elastin(found in tips of nose/ears), and Keratin(found in nails, beaks, etc.)
all imbedded in a matrix of muccopolysaccharides
Matrix of Muccopolysaccharides
Cartilage - glycoproteins
Bone - hydroxyapatite
Cartilage Types
Hyaline Cartilage (replacement bones)
Fibrocartilage (not flexible, provides strength, bundles of collagen)
Elastic cartilage (bundles of elastin fibers)
(all avascular aka no blood supply)
Cartilage Development
- Mesenchymal cells secrete mucopolysacharide matrix
- Inner layer of perichondrium contains matrix secreating mesenchymal that continue to deposit cartilage
- Once chondroblasts are surrounded by matrix, they stop secreting matrix and become a chondrocyte
Mesenchymal cells
secrete fibrous mucopolysaccharide matrix (i.e. fibroblast) during cartilage development
Perichondrium
Membrane surrounding cartilage, the inner layer of which contain mesencymal cells
Chondroblast
Mesenchymal cells that differentiate into cartilage secreting cells
Condrocyte
What chondroblasts become ones fully surrounded by matrix and stopping matrix secretion
Lacunae
where chondrocytes are located
Bone Types
Endochondral (required cartilaginous precursor)
Membranous (deposits directly in skin aka dermal bone)
Bone Development
- Cartilage impregnated w/ hydroxyapatite and Chondrocytes die
- Perichondrium proliferate and blood vessels invade cartilage
- Bone matrix secreted along disintegrating cartilage fiber axes
- Perichondrium -> periosteum and secretes layers of bone matrix that form outer covering of bone
Periosteum
What the perichondrium becomes during bone development to form layers of bone matrix to surround bone
Osteon
harvesian system of blood vessels + osteocytes
Osteocytes
In concentric layers of lamellae of bone, adult cells of osteoblasts interconnected by Canaliculi
Osteoclast
reabsorb bone during remodeling (i.e. if you break your bone)
Funtional Units of the Skeleton
- Head skeleton (cartilaginous brain case, visceral skeleton, dermal skeleton)
- Axial Skeleton (vertebral column, sternum and ribs)
- Appendicular Skeleton (pectoral and pelvic girdles and limbs)
Head Skeleton
Protects sense organs and brain
- Cartilaginous brain case aka Chondrocranium (endochondral bone)
- Visceral Skeleton aka Splachnocranium (embryonic jaws and gill arches
- Dermal Skeleton aka Dermatocranium (membrane bones)
Components of Head Skeleton
- Notochord - most ant. part
- Parachordal cartilages - 1 pair form basal plate (floor)
- Trabeculae - 1 pair fuse at ethmoid plate
- Occipital Cartilages - set of cartilages fuse at occipital arch
- Orbital Cartilages - 1 pair, behind the eyes descend to form side of brain case
- Sensory capsules - olfactory, optic, and otic
Foramina
Holes in the cartilage which allow nerves or blood vessels to pass through (ex. Foramina magnum = hole for spinal chord)
Parachordal cartilages
form the basal plate
Trabeculae
fuse together at ethmoid plate
Occipital cartilages
set of cartilages fuse at occipital arch
orbital cartilage
behind the eyes form side of brain case