Presentation 5: Skeletal System Flashcards
Connective Tissue
cartilage, bone, and adipose
all have extracellular fibers + proteins
provide support for organs and movement
Extracellular fibers (proteins)
Collagen (found in skin), Elastin(found in tips of nose/ears), and Keratin(found in nails, beaks, etc.)
all imbedded in a matrix of muccopolysaccharides
Matrix of Muccopolysaccharides
Cartilage - glycoproteins
Bone - hydroxyapatite
Cartilage Types
Hyaline Cartilage (replacement bones)
Fibrocartilage (not flexible, provides strength, bundles of collagen)
Elastic cartilage (bundles of elastin fibers)
(all avascular aka no blood supply)
Cartilage Development
- Mesenchymal cells secrete mucopolysacharide matrix
- Inner layer of perichondrium contains matrix secreating mesenchymal that continue to deposit cartilage
- Once chondroblasts are surrounded by matrix, they stop secreting matrix and become a chondrocyte
Mesenchymal cells
secrete fibrous mucopolysaccharide matrix (i.e. fibroblast) during cartilage development
Perichondrium
Membrane surrounding cartilage, the inner layer of which contain mesencymal cells
Chondroblast
Mesenchymal cells that differentiate into cartilage secreting cells
Condrocyte
What chondroblasts become ones fully surrounded by matrix and stopping matrix secretion
Lacunae
where chondrocytes are located
Bone Types
Endochondral (required cartilaginous precursor)
Membranous (deposits directly in skin aka dermal bone)
Bone Development
- Cartilage impregnated w/ hydroxyapatite and Chondrocytes die
- Perichondrium proliferate and blood vessels invade cartilage
- Bone matrix secreted along disintegrating cartilage fiber axes
- Perichondrium -> periosteum and secretes layers of bone matrix that form outer covering of bone
Periosteum
What the perichondrium becomes during bone development to form layers of bone matrix to surround bone
Osteon
harvesian system of blood vessels + osteocytes
Osteocytes
In concentric layers of lamellae of bone, adult cells of osteoblasts interconnected by Canaliculi