prescribing tasks Flashcards

1
Q

how are 8 week immunisations administered?

A

2 intramuscular injections and drops into the mouth for rotavirus

Hexavalent Vaccine (6-in-1):

Typically includes protection against Diphtheria, Tetanus, Pertussis (DTaP)
Haemophilus influenzae type b (Hib)
Inactivated Polio Vaccine (IPV)
Hepatitis B (HepB)
Oral Rotavirus Vaccine:

Rotavirus vaccines are usually administered orally as drops. There are two main types: RotaTeq and Rotarix. Both are designed to protect against rotavirus infections.
Other Injection Vaccines:

Pneumococcal Conjugate Vaccine (PCV13): This is an injectable vaccine to protect against diseases caused by the bacterium Streptococcus pneumoniae.

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2
Q

what vaccines are administered in the 8 week immunisations

A

1) the 6 in 1 vaccine which protects against diphtheria, tetanus, whooping cough, polio, Haemophilus influenzae type b and hep B
2) pneumococcal vaccine
3) rotavirus vaccine
4) men B vaccine

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3
Q

what are the different routes of administration of paracetamol?

A

oral tablet, capsule, suspension, orodispersible tablet, effervescent tablet, per-rectum, IV

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4
Q

what class of medications is mesalazine, what is it used for, and how does it work

A

aminosalicylates and it is for IBD –> decreases inflammation of GI tract by preventing leucocyte recruitment into bowel wall

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5
Q

in what ways can mesalazine be administered

A

oral tablets capsules or granules; liquid or foam enemas; suppositories

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6
Q

in what situations do you give oral mesalazine over rectal

A

rectal administration is for proctitis

oral is for when the UC has spread throughout the entire colon –> pancolitis

for left-sided disease (rectum + sigmoid have UC) you can still use rectal foam mesalazine

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7
Q

what is the traffic light system

A

a colour coded system that provides guidance on who is responsible for prescribing and monitoring different medications

red category are considered suitable only for a consultant or specialist to initiate and continue prescribing

Amber drugs are initiated in secondary care or another specialist setting, but are suitable for GPs to continue on-going prescribing under a shared care protocol

Green drugs are deemed suitable for initiation and ongoing prescribing in primary care.

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8
Q

what type of drugs would cause pre-renal damage?

A

the once which decrease perfusion to kidney –> NSAIDs, ACE-inhibitors, diuretics

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9
Q

what type of drugs cause intra-renal damage

A

the ones which are directly toxic to the glomerular interstitial tissue

antibiotics
diuretics
NSAIDs
ACE inhibitors

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10
Q

what type of drugs cause post-renal damage

A

the ones which cause urinary tract obstruction due to urinary retention or stone formation

anticholinergics may cause retention

sulphonamides (class of antibiotics) and methotrexate –> cause crystalluria

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11
Q

doxazosin vs tamsulosin

A

they are both alpha 1 blockers used in BPH but tamsulosin is more specific for bladder alpha receptor and it doesn’t cause vasodilation of the systemic blood vessels which also have the alpha receptors. Doxazosin is less selective –> also causes systemic vasodilation

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12
Q

when an old man takes tamsulosin for his LUTS and wants to get cataract surgery why is it important that he lets his doctor know that he is taking tamsulosin

A

because he can get Intraoperative Floppy Iris Syndrome and the surgeon must modify their surgical approach to avoid that

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13
Q

explain why a man can have reduced ejaculation if they are on tamsulosin

A

because of retrograde ejaculation –> because they are taking an alpha blocker the bladder sphincter is more relaxed so some of the ejaculate flows into the bladder instead of out

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14
Q

what is a big side effect of tamsulosin?

A

postural hypotension

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15
Q

what is the mechanism of action of methotrexate?

A

methotrexate competitively inhibits an enzyme of folic acid to prevent DNA synthesis

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16
Q

what do patients need to take if they are on methotrexate? how do they take it and why

A

patients need to take 5mg folic acid once weekly on a day when they are NOT taking methotrexate to counteract the antagonist actions of methotrexate on folate. this helps reduce side effects from methotrexate. giving the folic acid on the same day as methotrexate would reduce the effectiveness of methotrexate

17
Q

how do you monitor a patient on methotrexate for adverse drug reactions?

A

they need a FBC, renal and liver function tests before starting treatment and repeated every 1-2 weeks until therapy is stabilised (cuz you slowly up titrate the meds)

after the patients are monitored every 2-3 months

18
Q

would you give methotrexate to a pregnant woman?

A

NOOOO! it inhibits folate synthesis so teratogenic

19
Q
A