PrEP

Question 1

HIV Prevention Methods

Answer 1

Reduce sexually risky behaviors
Limit number of sex partners
Use condoms and barrier methods
Get tested with STDs
Post-exposure prophy
Ensure proper management in patients who are HIV+
PrEP

Question 2

CDC Clinical Eligibility for PrEP

Answer 2

Documented negative HIV test before prescribing, no signs/symptoms of acute HIV, normal renal function, no CI’ed meds, documented HBV infection/vaccination status

Question 3

Treatment for PrEP

Answer 3

Truvada (FTC/TDF 200mg/300mg) PO QD for up to 90 days

Question 4

Other services for PrEP (lab monitoring)

Answer 4

Assess renal function at 3 and 8 months, test for bacterial STIs every 3-6 months

Question 5

Indications of PrEP use by MSM: 4 requirements

Answer 5

Adult male or adolescent weighing >35kg
No acute or established HIV infection
Any male sex partner in the last 6 months
Not in a monogamous relationship with a recently tested, HIV-negative man

Question 6

Indications of PrEP use by MSM: they have to meet at least 1 of these 3 criteria

Answer 6

Any anal without a condom in the last 6 months
Bacterial STIs in the last 6 months
High number of sex partners/commercial sex worker

Question 7

Indications of PrEP use by heterosexual men and women: 4 requirements

Answer 7

Adult or adolescent weighing >35kg
No acute or established HIV infection
Any sex with the opposite sex partner in the last 6 months
Not in a monogamous relationship with a recently tested, HIV-negative partner

Question 8

Indications of PrEP use by heterosexual men and women: they have to meet at least one of these criteria

Answer 8

-A bisexual male
-Infrequent condom use with ≥1 partner(s) with unknown HIV status at substantial risk of HIV infection
-An ongoing relationship with an HIV+ partner
-Bacterial STI in the last 6 months
-High number of sex partners/commercial sex worker
In high HIV prevalence area or network

Question 9

Indications for PrEP use by people who inject drugs: 3 requirements

Answer 9

Adult or adolescent weighing >35kg
No acute or established HIV infection
Any injection of illegal drugs in the part 6 months

Question 10

indications of PrEP use by people who inject drugs: must meet at least 1 of these criteria

Answer 10

Any sharing of injection or drug preparation equipment in the past 6 months
Risk of sexual acquisition

Question 11

Truvada prescribing points

Answer 11

Provide script or refill authorization for no more than 90 days
Patients MUST be reassessed every 90 days for continued use
Can be taken indefinitely as long as the individual continues to be at risk for HIV infection and isn’t experiencing ADEs

Question 12

Truvada ADEs

Answer 12

Diarrhea, nausea, fatigue, headache, dizziness, depression, insomnia, abnormal dreams, rash, abdominal pain, weight loss

Question 13

Importance of adherence to Truvada

Answer 13

The more adherent a patient is, the better it will work