Prenatal Care: Routine Flashcards
When to start measuring fundal height?
20 weeks
Pre-pregnant size and shape of uterus?
size of fist/pear
Size and shape of 12 week uterus?
palpable at the top of the pubis symphysis
size of grapefruid
Size and shape of 16 week uterus?
1/2 way between the pubis symphysis and umbilicus
Size and shape of 10 week uterus?
at umbilicus
Size and shape of 36 week uterus?
At xiphoid process
Size and shape of 36-40 week uterus?
lower than xiphoid process - lightening
What is Nagel’s rule?
LMP - 3 months + 7 days = EDD
When is Hcg detectable in urine? What is the value in the plasma typically at that point?
Begins to rise 8 days after ovulation
8-11 days after fertilization hCG is detectable in urine
In plasma at that point: 50-250 mIU/L
How often does hCG double in the first 5-6 weeks?
every 1.5-3 days (typically draw 48 hours apart and expect doubling)
How often does hCG double in weeks 7&8?
every 3-3.5 days
When does hCG peak?
week 8-10
What is avg efw at 30 weeks?
3 lbs and will gain about 0.5 lbs weekly after that :)
What do you measure in a dating u/s < 13+6?
CRL
When do you change EDD based on u/s and LMP discrepancy prior to or at 8+6?
More than 5 days
When do you change EDD based on u/s and LMP discrepancy prior to or at 13+6?
More than 7 days
What do you measure at a dating u/s at 14 weeks and beyond?
BPD (biparietal diameter), HC (head circ), AC (abd circumference), FL (femur length)
When do you change EDD based on u/s and LMP discrepancy at 14+0 to 15+6?
More than 7 days
When do you change EDD based on u/s and LMP discrepancy at 16+0 to 21+ 6?
More than 10 d
When do you change EDD based on u/s and LMP discrepancy at 22+0 to 27+6?
More than 14 d
When do you change EDD based on u/s and LMP discrepancy at 28+0 and beyond?
More than 21 d
What are Presumptive Indicators of Pregnancy?
Subjective things, reported by patient
Amenorrhea
N/V
fatigue
urinary frequency
Breast tenderness
skin pigment changes
sustained BBT
Fetal movement felt by patient (quickening)
What are Probable Indicators of Pregnancy?
Objective, seen by provider, but not POSITIVE, could be explained by other things:
Abdominal enlargement
expression of colostrum
cervical softening
Hegar’s sign (softening of uterus)
Goodell’s sign (softening of cervix)
Chadwick’s sign (blue cervix)
Ballottement (palpate cervix and feel rebound)
BH ctx
Palpation of fetal outline/fetal movement by provider
+urine or +plasma hcg
Chadwicks sign
blue/purple cervix
probable pregnancy sign
6-8 weeks
Goddell’s sign
softening of cervix (6-8 weeks)
probable pregnancy sign
Hegar’s sign
softening of uterus
probable pregnancy sign
POSITIVE Pregnancy signs
Objective and can’t be explained by other things
(1) auscultation of FHR
(2) visualization of fetus on u/s
When does quickening usually occur in a primip?
about 20 weeks (partner usually can’t feel for another month)
feel like flutters
When does quickening usually occur in a multip?
about 18 weeks (partner usually can’t feel for another month)
feel like flutters
When does fetal movement become more regular?
24 WEEKS
When to start kick counts?
3rd trimester, if it is needed
before that, baby is not yet developmentally there
What does Maternal Serum AFP (MSAFP) test for?
Neural tube defects (spind bifida, anencephaly, gastroschisis, omphalocele)
When can we draw AFP?
15+0 to 21+6
What does Non-Invasive Prenatal Testing (NIPT) aka cell-free DNA Screen for?
Aneuploidy: trisomy 21, trisomy 18, trisomy 13, monosomy X (turner’s syndrome), Klinefelter (XXY), triple X (XXX), Jacob’s Syndrome (XYY)
Microdeletions: prader-willi, angel man, cri du chat, etc
Biologic Sex of the baby
IT IS THE LOWEST false positive rates of all the screenings
When can NIPT be done?
10 weeks until the end of pregnancy
This is the earliest screening option
1-2 week turn around time
Disadvantages of NIPT?
It is just screening - need to f/u with diagnostic testing
If multiple pregnancies: not specific to the fetus (can’t say if it pertains to one or both babies)
Can be expensive
Zygote
diploid cell with 46 chromosomes that results from the fertilization of the ovum by a spermatozoan
Blastomere
Mitotic division of the zygote (cleavage) yields daughter cells called blastomeres
Morula
Solid ball of cells formed by 16 or so blastomeres, enters uterine cavity 3 days post fertilization
Blastocyst
after the morula reaches the uterus, a fluid accumulates between blastomeres, converting the morula to a blastocyst; inner cell mass at one pole becomes the embryo and the outer cell mass is the trophoblast
Embryo
stage in prenatal development between the fertilized ovum and the fetus (between the 2nd and 8th week inclusive)
Fetus
developing after the embryonic stage
When does implantation occur?
Blastocyst implants into the endometrium about day 6-7 after fertilization
How are oxygen and glucose transported across the placenta?
facilitated diffusion
What vessels are in the umbilical cord?
2 arteries: Carry deoxygenated blood from fetus to placenta
1 vein: carries oxygenated blood from placenta to fetus
Wharton’s jelly
connective tissue that surrounds and protects the umbilical cord
What are the risks if the umbilical cord is extremely short?
abruptio placentae or uterine inversion
What are the risks of a really long umbilical cord?
vascular occlusion by true knots and thrombi
What is Polyhydramnios?
an excess of amniotic fluid
Amniotic fluid index (AFI) >/= 24 cm
Maximum vertical pocket (MVP) >/= 8
S/s of polyhydramnios?
S>D, difficulty auscultating FHR, difficulty palpating fetal parts
Cause of polyhydramnios?
50-60% idiopathic
Associated with: fetal anomalies, fetal infection, twin to twin transfusion syndrome, maternal DM (including GDM), isoimunization, multiple gestation
What risks are caused by polyhydramios?
increased risk of PPH, PTL, cord prolapse with ROM, associated with erythroblastosis
Management of Polyhydramnios?
Treat only if symptomatic and if benefits outweigh risks
Monitor with serial NSTs and BPPs, starting at 34 weeks
(1) Amniocentesis: to reduce fluid volume if polyhydramnios is severe (AFI > 35 cm), amniotic fluid can also be tested for fetal lung maturity and chromosomal studies
(2) Indomethacin: impairs production of lung liquid, increased fluid movement through fetal membranes or decreased fetal urine production
Oligohydramnios
decreased amniotic fluid volume
Amniotic Fluid Index (AFI) </= 5 cm
MVP < 2
Conditions associated with oligohydramnios:
Fetal:
- urinary tract obstruction or renal agenesis
- chromosomal abnormalities
-congential anomalies
-growth restriction
-demise
-post-term pregnancy
-ROM; PROM
Placental:
-abruption
-twin-to-twin transfusion syndrome
Maternal:
-Uteroplacental insufficiency
-hypertensive disorders
-DM
Drugs:
- Prostaglandin synthesis inhibitors
-ACE-I
Prognosis for early-onset oligo
DM poor outcome, risk of pulmonary hypoplasia increased; if d/t PROM increased still birth risk
Prognosis for late-onset oligo
more c/s for fetal distress
Management of oligo
u/s eval for fetal anomalies and growth restriction
Amnioinfusion in IP period for tx of repeated variable decels
When is the period of organogenesis?
begins in 3rd week after fertilization through 8 weeks
all major organ systems are formed except for lungs
4th week: partitioning of heart, arm/leg buds, body stalk that becomes umbilical cord forms
6th week: head much larger than body, heart is completely formed, fingers and toes present
How early is urine hcg positive?
As early as 1 week after conception
What hormones do the corpus luteum secrete?
Progesterone; corpus luteum persists until about 12 weeks under influence of hcg, it is responsible for the secretion of progesterone to maintain endometrium and pregnancy until the placenta takes over production
Epulis
focal swelling of gums, resolves after birth
Pregnancy-related mouth changes
gingivitis is common, may cause gum bleeding
increased salivation
Epulis
Pregnancy-related esophageal changes
decreased LES pressure and tone
widening of hiatus with decreased tone
heartburn is common