Postpartum Flashcards

1
Q

Early Postpartum
What is normal temperature?
What is abnormal temperature?
Differentials for abnormal temp?

A

Normal: 98.6-100.4, stabilizes during the first 24 hours postpartum
Abnormal: > 100.4
DDX for abnormal: infection, pulmonary embolism

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2
Q

Early Postpartum
What is normal pulse?
What is abnormal?
Differentials for abnormal pulse?

A

Normal: 65-80
Abnormal: >80
DDx: infection, increased blood loss, pulmonary embolism

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3
Q

Early Postpartum
What is normal BP?
What is abnormal BP?
Differentials for abnormal BP?

A

Normal: same as pre-pregnant, although transient increase in BP as much as 5% of baseline in 4 days after delivery
Abnormal: >140/>90: DDX postpartum hypertensive disorder, PEC
<90/<60: DDX blood loss, med reaction

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4
Q

Early Postpartum
Normal Neurologic assessment
Abnormal Neurologic assessment

A

Normal: A&O x3
Abnormal: disoriented, excessive sedation

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5
Q

Early Postpartum
Normal Lung assessment
Abnormal Lung assessment

A

Normal: No SOB, able to breathe without difficulties, clear to auscultation
Abnormal: SOB, adventitious breath sounds on

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6
Q

Early Postpartum
Normal Cardio assessment
Abnormal Cardio assessment

A

Normal: No CP, RRR
Abnormal: chest pain, palpitations, tachycardia

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7
Q

Early Postpartum
Normal Breast assessment
Abnormal Breast assessment

A

Normal: Nipples may be sore from nursing, but NOT painful; colostrum and breast fullness x3-5 days
Abnormal: Painful,cracked, bruised, blistered, bleeding nipples; no breast filling by day 5

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8
Q

Early Postpartum
Normal GI/Abdomen assessment
Abnormal GI/Abdomen assessment

A

Normal:
- eating and drinking without difficulty
- Return of bowel movement day 2-3 PP
- Presence of bowel sounds
- Decreased muscle tone
- Diastasis recti is expected
- Firm fundus and midline; level of fundus appropriate according to process of involution
- surgical scar is well approximated, without s/s of infection

Abnormal:
- nausea and vomiting, abdominal pain, constipation or diarrhea
- distended abdomen, unable to palpate uterus
- Fundal height not midline and level is increasing not according to PP day
- surgical scar is not well approximated, showing signs of infection and dehiscense

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9
Q

Early Postpartum
Normal Urinary assessment
Abnormal Urinary assessment

A

Normal:
- voiding spontaneously and without difficulty,
- diuresis,
- mild external burning, retention, incontinence, lack of sensation or urge to void is common in first 2 days

Abnormal:
- dysuria, persistent retention or incontinence, distended bladder, CVA tenderness

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10
Q

Early Postpartum
Normal Perineum assessment
Abnormal Perineum assessment

A

Normal:
- mmild erythema, bruising, edema;
-laceration/episiotomy repair is well approximated and without drainage,
-lochia decreasing in amount each day

Abnormal:
-worsening perineal tenderness, erythema, edema,bruising
- Presence of hematoma
- laceration/episiotomy repair is not well approximates, showing signs of separation
- malodorous lochia; excessive amounts with clots, soaking pads

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11
Q

Early Postpartum
Normal Anus assessment
Abnormal Anus assessment

A

Normal: hemorrhoids may be present, pink in appearance
Abnormal: hemorrhoids deep blue or purple

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12
Q

Early Postpartum
Normal LE assessment
Abnormal LE assessment

A

Normal: muscle soreness from positioning in labor, bilateral/symmetric edema
Abnormal: unilateral leg pain, unilateral calf tenderness, one leg more edematous than the other

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13
Q

What is uterine involution?

A

Process of the uterus returning to the pre-pregnant state - results from reduction in cell size (not number)

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14
Q

What is the normal process of uterine involution?

A
  • Immediately after delivery: uterus contracts to about the size of a grapefruit, located halfway between umbilicus and symphysis pubis
  • By 12 hours post-delivery: uterus is at the level of the umbilicus; fundus should be midline of the abdomen, if displaced to the side, may indicate a full bladder
  • The fundus then descends about 1 cm per day
  • By 2 weeks: uterus no longer palpated abdominally
  • By 6 weeks: uterus returns to slightly larger than pre-pregnant state
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15
Q

What is Lochia:

A

Vaginal discharge in the post-partum period. Consists of the breakdown of myometiral placenta bed, eschar and decidual cells.

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16
Q

What are the 3 stages of lochia discharge?

A

Rubra, Serosa, Alba

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17
Q

Lochia Rubra:

A

Lasts: 3-7 days
Color: Red or red-brown
Description: Fleshy odor, contains superficial layer of decidua that has sloughed off the uterus, debris (cellular remains from vernix, lanugo, mec, necrotic placenta remains)

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18
Q

Lochia Serosa

A

Lasts: from day 14-21
Color: Pinkish-brown color
Description: Serous to serosanguinous secretion; contains blood, cervical mucus, erythrocytes, leukocytes, decidual tissues

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19
Q

Lochia Alba

A

Lasts: Until cessation of flow in about 4-6 weeks postpartum
Color: Yellowish to white discharge
Description: Flow increases with additional activity initially but decreases progressively

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20
Q

Normal Transition of the Cervix postpartum?

A
  • Immediately after vaginal birth the cervix appears edematous dilated 3-4 cmand bruised, may have lacerations
  • Day 2-3 PP: Continues to be dilated 2-3 cm
  • By day 7: 1 cm
  • By 4 weeks: No longer dilated
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21
Q

What does Multiparous Cervix look like at completion of involution?

A

External os does not return to its pre-pregnant appearance, remains somewhat wider with transverse opening, resembling a fish mouth

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22
Q

Normal Transition of the vagina Postpartum?

A

Immediately PP: edematous, relaxed, sometimes bruised with decreased tone
By 3-4 weeks PP: rugae return; edema, vascularity, and bruising decrease
By 6-10 weeks postpartum, vaginal epithelium
** Decreased Lubrication can lead to pain with sex, especially with breastfeeding***

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23
Q

Normal Transition of the Perineum Postpartum:

A

Immediately after birth: edematous with decreased tone, laceration and episiotomy repair should be well approximated
7 days PP: skin should appear healed with only linear scarring by 6 weeks

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24
Q

Normal Transition of Breast postpartum:

A
  • colostrum is produced upon birth of baby, may even have colostrum production in 3rd trimester
  • engorgement occurs approximately 72 hours after birth
  • milk ejection reflex develops within the first 1-2 weeks
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25
Q

Normal transition of the hematologic system postpartum:

A

Immediately postpartum in the fist hours post birth: Cardiac output increases 60-80%
Over first 48 hours: diuresis occurs, plasma volume decreases and cardiac output normalizes by 2 weeks

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26
Q

Normal changes of Renal system PP:

A

Diuresis occurs within first 5 days as result of extravascular fluid shifts
Bladder can be hypotonic and edematous immediately after the birth: resolves in 24 hours
Prolonged labor, trauma to vulva, urethra or bladder, use of anesthesia during c/s can cause urinary retention

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27
Q

Normal Weight loss/caloric intake pp:

A

Caloric intake at least 1800 calories per day +500 cal if breastfeeding (more if twin breastfeeding)
No more than 4.5 lb/month of weight loss

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28
Q

Normal abdominal changes PP:

A

-decreased peristalsis in first 24 hours pp
- AST/ALT return to pre-preg levels by week 2
- diastasis recti found in 75-80% of pp women
-striae common

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29
Q

Endocrine changes in breastfeeding women:

A
  • Lactation is stimulated and prolactin and oxytocin are secreted
  • By negative feedback, ovulation and menstruation are inhibited by increased prolactin, resulting in estrogen suppression
  • If exclusively breastfeeding, there is a 1-3% change of ovulation within the first 6 months PP
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30
Q

When will Menses return after weaning breastfeeding?

A
  • generally ovulation 14-30 days after weaning, first menses 14 days later!
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31
Q

What is efficacy of LAM?

A

1-3% chance of ovulation in first 6 months PP if exclusively breastfeeding

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32
Q

Endocrine changes in non-breastfeeding women

A

Prolactin levels fall after initial engorgement
Hormonal shifts to stimulate ovulation begin 3-4 weeks pp
First menses: 6-8 weeks pp, 70% by 12 weeks

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33
Q

When to expect return to menses if NOT breastfeeding (never started)?

A

Avg: 6-8 weeks pp, 70% by 12 weeks

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34
Q

When to give Rhogam?

A

Anti-Rho(D) immune globulin (Rhogam) should be given within 72 hours of birth if mom is Rh neg and baby is Rh +

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35
Q

Vaccines to give immediately PP if not already received/immune?

A

Tdap, MMR, varicella, Flu, HPV, COVID

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36
Q

Common PP Discomfort: Involutional PAIN
Comfort measures?

A
  • likely to increase with each subsequent birth and with nursing
    NONPHARM:
  • maintain empty bladder and bowels
  • relaxation and breathing techniques
  • changing positions, sitting up, walking,
  • applying heat,
  • using abdominal support binder, lying flat on the abdomen

PHARM:
- ibuprofen
- acetaminophen
-Avoid opioids (some women are ultrametabolizers of codeine, which causes rapid conversion to morphine, which puts babies at risk of respiratory depression)

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37
Q

Common PP Discomfort: Diuresis
Comfort measures?

A

stay well hydrated to prevent dehydration
Maybe sleep with a towel under you/change of clothes nearby so you can quickly change out of wet clothes

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38
Q

Common PP Discomfort: Breast Engorgement
Comfort measures?

A
  • Initiate breastfeeding early and often
  • assess that infant is positioned correctly and properly latched
  • at times, infants can’t latch to severely engorged breasts –> instruct patient to express small amount of milk manually before each feeding to soften the areola and allow the infant to latch properly
  • can use pump to assist with softening the breasts before feeding by releasing enough milk for infant be able to latch
  • avoid excessive pumping, as this increases breastmilk production and worsens engorgement
  • supportive Bra
  • warm compress or warm shower before feeding

IF bottle feeding:
- tight bra
- ice pack
-analgesics
- reassurance about time limitation
- cold cabbage leaves in bra for comfort

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39
Q

Common PP discomfort: Perineal Pain
Comfort measures?

A
  • evaluate by REEDA (redness, edema, ecchymosis, discharge, approximation)

Topical meds/treatment:
- witch hazel pads
- dibucaine, benzocaine
- ice packs for first 24 hours
- sitz baths after 24 hours
- topical anesthetics

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40
Q

Common PP Discomfort: Constipation
Risk factors?
Comfort Measures?

A

Risk factors: lack of ambulation in labor and pp period (esp after c/s); decreased intestinal peristalsis due to anesthesia, narcotic use for pain

Comfort:
- increase fluids, fiber
- stool softener
-encourage ambulation
- laxatives if needed

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41
Q

Common PP Discomfort: Hemorrhoids
Prevention?
Comfort?

A

Prevention: bowl regimen of scheduled use of stool softeners to avoid constipation; avoid straining with bowel movement
Comfort: ice packs, topical anesthetics, referral if thrombosed

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42
Q

Postpartum blues

A

-affects 80% of women
- begins within 3-5 days of birth, concurrent with profound hormonal shifts
- Very labile emotions (giddiness, sadness, crying)
- generally time-limited over 1-2 weeks
- supportive, sensitive care is usually all that is needed

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43
Q

Postpartum Depression: Definition

A

Depression occurring anytime within 4 weeks after childbirth and up to 12 months

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44
Q

Risk factors for Postpartum Depression:

A
  • hx of depression/anxiety, esp if untreated in pregnancy
  • genetic
  • social factors: IPV, prior abuse, lack of social support, negative life events
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45
Q

When is the most common onset of symptoms of PP depression?

A

usually 4-6 weeks, worsens overtime
can be anytime within 12 month after birth

46
Q

Symptoms of PP depression:

A
  • sleep disturbance
  • feeling overwhelmed
  • anxiety
    -irritability
  • unable to perform ADLs- symptoms can be incapacitating to women
  • preoccupation and obsession with infant health
  • can have suicidal, infanticidal, homicidal ideation
  • apathy toward self/infant
  • symptoms DO NOT improve over time, likely worsen
47
Q

What other illnesses should you rule out with PP depression?

A
  • postpartum thyroiditis
  • anemia
  • infection
  • sleep deprivation
48
Q

Diagnosis of PP depression?

A

At least one of the following 2 symptoms:
(1) depressed mood
(2) loss of interest or pleasure

In addition 4+ of the following symptoms:
1. depressed mood most of the day, nearly every day (feels empty, sad, hopeless)
2. Marked diminished interest or pleasure in all or almost all activities
3. Significant unintentional weight loss or decrease in appetite
4. Insomnia or hypersomnia
5. Psychomotor agitation or retardation
6. fatigue/loss of energy
7. feelings of worthlessness or excessive or inappropriate guilt
8. Diminished ability to think or concentrate
9. suicidal ideation with or without a plan

49
Q

Treatment for PP depression:

A
  • consult psych team
  • ensure safety of mom and infant
  • Psychosocial strategies including peer support and counseling
  • CAM: omega 3 fatty acids, folate, st john’s wort, bright light therapy, exercise, massage, acupuncture
    Pharm: SSRIs are 1st line–> most SSRIs pass to breastmilk, but are usually compatible with breastfeeding a healthy, full-term infant
50
Q

Postpartum psychosis:

A

s/s:
- disorganized thinking, bizarre speech and behavior
- hallucinations with auditory or visual perceptual disturbances
- delusions

THIS Is a PSYCH EMERGENCY:
- need psych team
-hospitalization usually
- patient may be a danger to self, infant, others

51
Q

Return to ovulation in non-breastfeeding patients:

A

39 days pp

52
Q

Return to ovulation in Breastfeeding patients

A

varies depending on frequency and duration of breastfeeding

53
Q

Return to sexual activity

A

Clinicians typically recommend pelvic rest x 4-6 weeks, but studies have shown that 50% of women resume sexual activity before pp visit

54
Q

How long does hypercoaguable state last pp?

A

PP patients are in a hypercoaguable state for 3-4 weeks pp
Estrogen containing conctraception needs to be avoided during this period

55
Q

How long to wait postpartum before taking CHC (with estrogen)??

A

42 days (6 weeks) d/t hypercoaguable state

56
Q

What types of BC are OK in PP period?

A

Cu-IUD and LNG-IUD can be given in postpartum period at any time, even immediately after placenta is delivered; they are only contraindicated with PP sepsis!

Implant, Depo, Pop can also be given at any time in pp period, controversy about effects on lactation

Tubal Ligation in hospital, generally consent prior to birth

57
Q

What needs to happen for LAM method to be effective?

A

Exclusive breastfeeding
feeding at least q 4 hours during day and 6 hours at night
has not started solid foods for any meals
infant less than 6 months old
no menses

If a women does not meet this criteria, choose another method*

58
Q

If had GDM, what test does pt need at 6 weeks pp?

A

fasting, 2-hour 75 g glucose tolerance test

59
Q

Diagnosis of Urinary Retention

A
  • Inability to void spontaneously within 6-8 hours after birth or after removal of urinary catheter after delivery
    -post-void residual urine of > 150 mls
  • Palpable bladder
  • fundus of uterus displaced and not midline in abdomen
60
Q

Risk Factors for Urinary retention

A
  • epidural anesthesia
  • operative vaginal delivery
  • episiotomy/laceration, esp periurethral lac
  • LGA infant
  • Primpip
61
Q

Complications of Urinary Retention

A

UTI
bladder dysfunction

62
Q

Management of Urinary Retention

A

Non-pharm:
- give pt privacy on the toilet to relax, not feel pressure to void
- few drops of peppermint oil in toilet water or bed pan
- sound of running water
- place hand in warm water

PHARM:
- intermittent catheterization
- indwelling catheter
- consult urology

63
Q

What is the definition of a postpartum fever?

A

Temp of greater than or equal to 100.4 x 2 during postpartum days 2-10

64
Q

What is the differential diagnosis for postpartum fever?

A

Most Common:
- Endometritis
- UTI
- Wound infection

Less common:
- transfusion reaction
- drug reaction
- septic pelvic thrombophlebitis (SPT)

65
Q

Endometritis Definition

A

Uterine infection/inflammation or lining of uterus

66
Q

Endometritis s/s

A

general malaise/flu-like symptoms
fever
tachycardia
abdominal pain
malodorous lochia

67
Q

Risk factors for endometritis:

A
  • prolonged ROM
  • prolonged labor
  • multiple cervical exams
  • c/s
  • choriomanionitis
  • lower genital infection with GBS, Chlamydia, mycoplasma hominis, ureaplasma urealticum, Gardernella vaginalis
68
Q

Treatment for endometritis:

A

(1) Gold standard: clindamycin and gentamicin
(2) Vancomycin should be added if staphylococcus aureus is suspected

69
Q

Risk factors of abdominal incision infection

A
  • obesity
    -DM
  • corticosteroid therapy
  • immunosuppression
  • anemia
  • hypetension
    -hematoma
70
Q

Treatment for abdominal incision infection:

A

antimicrobials
surgical drainage

71
Q

Risk factors for Wound dehiscense

A
  • wound infection
  • obesity
72
Q

Treatment for wound dehiscense

A
  • treat underlying infection
  • secondary closure of the incision in the operating room
73
Q

Definition of Perineal Infection

A

Infection of the perineum due to infected episiotomy or lac, can lead to dehiscence of the repair

74
Q

Perineal Infection treatment:

A
  • drain and debridement
  • antimicrobial therapy
  • wound care
  • secondary repair when episiotomy or lac has healed
75
Q

What is Septic pelvic thrombophlebitis?

A

septic phlebitis along venous route,then causing thrombosis

76
Q

Clinical manifestation of septic pelvic thrombophlebitis?

A

-pain in one or both lower abdominal areas
-chills

77
Q

How to diagnose septic pelvic thrombophlebitis?

A

CT, MRI

78
Q

What is the leading cause of maternal mortality worldwide?

A

Postpartum hemorrhage (PPH)

79
Q

What is the ACOG definition of PPH?

A
  • EBL of 1000 mL regardless of route of delivery
  • Blood loss accompanied by s/s of hypovolemia within 24 hours after birth
80
Q

Traditional def of PPH

A

EBL of 500 mls or more after vaginal birth, EBL of 1000 mls or more after c/s

81
Q

Risk factors for PPH

A
  • prolonged labor
  • prolonged use of oxytocin
  • chorioamnionitis
  • high parity
  • twins, multiple gestation
  • polyhydramnios
    -macrosomia
    -operative vaginal delivery
  • precipitous delivery
82
Q

Etiology of Primary PPH:

A

TONE: uterine atony: MOST COMMON 70-80%
TRAUMA: laceration, hematoma
TISSUE: retained placenta
THROMBIN: coagulation defects

Placenta accreta and uterine inversion can also cause PPH

83
Q

What is Primary PPH

A

Occurs within 24 hours after delivery

84
Q

What is Secondary PPH

A

Occurs between 24 hours and 12 weeks postpartum

85
Q

PPH: what are s/s of uterine atony?

A

soft, boggy uterus

86
Q

How to manage PPH cause by uterine atony?

A

Empty bladder, bimanual exam to remove intrauterine clots, perform fundal/uterine massage, administer uterotonics (oxytocin, methergine, hemabate, miso), intrauterine tamponade if needed

87
Q

How to manage PPH cause by trauma?

A

Identify the source of lac/bleed: vaginal, vulvar, periclitoral, perineal, genital tract hematoma
- repair lac
- hematoma may need incision and drainage
- arterial embolization

88
Q

S/S of PPH hemorrhage caused by obstetric trauma

A
  • bleeding wound
  • patient may complain of labial, rectal, pelvic pressure or pain (hemotoma esp)
  • abnormal vital signs
89
Q

How to manage PPH caused by retained placenta?

A

Diagnosis: visual insepction of placenta, u/s, intrauterine manual exam
Mgmt: removal of retained placenta, curettage with u/s guidance

90
Q

Etiology of secondary PPH

A

Subinvolution
Retained placenta/products of conception
Infection
Coagulation defects
- Acute coagulopathy: caused by placental abruption, ambiotic fluid embolism, DIC, managed by volume replacement and initiating transfusion protocol

91
Q

What are montgomery tubercles

A

sebaceous glands on the areola of the breast that provide protective secretion and lubrication to the nipple

92
Q

Lactogenesis I:

A

WHEN: Occurs early pregnancy to 3rd day postpartum
WHY: Hormones of Pregnancy
WHAT: secretion of small amount of colostrum
- Approx 100 mls of breastmilk is produced on day 1 pp
- contains high concentration of immunoglobulins

93
Q

Lactogenesis II

A

WHEN: 2-4 days PP
WHY: placenta delivers –> decrease in progestin hormone concentration, increase in prolactin hormone concentration
WHAT: Volume of milk increases
- about 500 mls of breastmilk is produced on pp day 4
- copious milk production begins
- typically referred to as “milk coming in”

94
Q

Lactogenesis III

A

WHEN: begins between 7-14 days pp
WHY: Milk production depends on supply-demand relationship
- frequent milk transfer —> suckling stimulates the nipple and areola –> message sent to hypothalamous to secrete prolactin and oxytocin hormones
WHAT: mature milk is established, maintenance of milk supply

95
Q

What does prolactin do in Breastfeeding?

A

stimulates milk production

96
Q

What does oxytocin do in breastfeeding?

A

stimulates the contraction of myoepithelial cells; this contraction of cells causes milk ejection
AKA let-down reflex

97
Q

Contraindications to breastfeeding?

A

Maternal infection:
-HIV
-Active herpes lesion on nipple
-flu
-untreated TB
-Varicella infection developed 5 days prior to birth and 2 days after birth

Illicit drug use
Specific meds
- anticonvulsants
- chemo/radiation
-statins
- retinoids
-some antiretrovirals

98
Q

Breast Engorgement
How to prevent
How to treat

A

Prevention:
- proper breastfeeding positioning and attachment
- emptying one breast at each feed
- alternating which breast is offered first
- frequent milk transfer

Treatment:
- Acupuncture
-hot/warm pack prior to feeding followed by cold pack after feeding
- Cold cabbage leaves after feeding
- breast masage
- hand expression

99
Q

Insufficient Milk Supply
How to evaluate
How to treat

A

Eval:
- eval for medical causes of low milk, medication
- assess frequency and effectiveness of milk removal and transfer

Treat:
- increase frequency of feeds
- galactagogues
- eliminate meds that may decrease supply

100
Q

Galactagogues

A

CAM:Fenugreek, goat’s rue, milk thistle, oats, dandelion, seaweed, blessed thistle, fennel seeds, beer (hops/barely, but alcohol can decrease supply)

PHARM:
- domperidone: warning - increases QT interval and implicated in ventricular arrhythmias and sudden cardiac death
- Metoclopramide: warning: CNS sedation, depression, extrapyramidal symptoms

101
Q

Mastitis Diagnosis:

A
  • Erythematous, edematous, wedge-shaped area in the breast, typically unilateral
  • fever >/= 101.3
  • flu-like symptoms
102
Q

Mastitis risk factors

A
  • damaged nipples
    -infrequent feedings
  • ineffective milk transfer and removal; (poor latch, uncoordinated suck)
  • Oversupply of milk
  • rapid weaning
    -bra too tight
  • maternal fatigue
  • hx of mastitis
103
Q

Mastitis tx:

A

Analgesia:
- NSAIDs
- alleviating pain may help pt relax and facilitate let-down

ABX:
- dicloxacillin or flucloxacillin 500 mg PO QID x 10-14 days
- Keflex (cephalexin) 500 mg QID x 10-14 days
- If PCN allergic: clindamycin 300 mg QID or erythromycin 250 mg QID x 10-14 days

** should improve/resolve within 48 hours of starting antibiotics**

104
Q

Breast abscess

A

collection of pus in breast, surrounded by inflammation

105
Q

Breast abscess diagnosis:

A

PE and u/s

106
Q

Breast Abscess likely organism

A

S. aureus

107
Q

Management of Breast Abscess

A

surgical drainage, needle aspiration, abx

108
Q

Raynaud’s phenomenon of the breast:
What is is?
S/S
Treatment

A

WHAT: Vasospasm of the nipple after breastfeeding or when nipples are exposed to cool air
S/S:
- nipple color changes to purple or blanches, may be unilateral or bilateral
- severe pain - sharp/burning sensation

Tx: nifedipine, avoid exposure to cold air

109
Q

Fungal infection of breast:
What is it?
S/S
Treatment

A

WHAT: infecting organism candida, diagnosis is based on history of PE
S/S:
- infant may have thrush or diaper rash
- shiny and red nipple and areola
- flaky skin around nipple
- burning, itching, stabbing pain like “shards of glass” in breast

Tx:
- topical nystatin, miconazole, or clotrimazole
- APNO cream (mupirocin 2% ointment, betamethasone 0.1% ointment, miconazole 2%)
-Gentian violet 1% in 10% alcohol to nipple x 4 days

110
Q

What is the max dose of acetaminophen per day for an adult?

A

4000 mg/day

111
Q

What is the max dose of ibuprofen per day for an adult?

A

3200 mg/day