PRELIM LEC: QUALITY CONTROL AND QUALITY ASSURANCE IN HEMATOLOGY Flashcards

1
Q

Is the broader concept, encompassing
preanalytical, analytical, and postanalytical
variables

A

QUALITY ASSURANCE

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2
Q

Coordinated effort to organize laboratory activities

A

QUALITY ASSURANCE

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2
Q

Control and monitor

A

QUALITY ASSURANCE

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3
Q

Provide best service to patient and doctor

A

QUALITY ASSURANCE

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4
Q

Evaluate and monitor the accuracy and
precision of test performance over time

A

QUALITY CONTROL

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5
Q

To detect errors

A

QUALITY CONTROL

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6
Q

Same matrix as px specimen

A

CONTROL

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7
Q

Predetermined assay value

A

CONTROL

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8
Q

To identify for any contamination

A

CONTROL

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9
Q

Essentially pure form

A

PRIMARY STANDARD

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10
Q

Calibrate instrument

A

PRIMARY STANDARD

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11
Q

Time-consuming

A

PRIMARY STANDARD

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11
Q

Certified reference material

A

PRIMARY STANDARD

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12
Q

Fixed and known composition

A

PRIMARY STANDARD

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13
Q

Analyte concentration ascertained by reference to a primary standard

A

SECONDARY STANDARD

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14
Q

Preserved human or surrogate cell
suspension

A

CALIBRATOR

15
Q

Closeness of results obtained from repeated analysis of same specimen

16
Q

Closeness to the true or actual value

17
Q

Reproducibility

18
Q

Assess change

A

DELTA CHECKS

19
Q

Compare results from spx analysis with result of previous spx

A

DELTA CHECKS

20
Q

Same analyte, same patient

A

DELTA CHECKS

21
Q

Extent to which a method is able to maintain
accuracy and precision over time

A

RELIABILITY

22
Q

Reference range

A

REFERENCE INTERVAL

23
Range of values of analyte in health individuals
REFERENCE INTERVAL
24
Proportion of px with the disease with positive result
DIAGNOSTIC SENSITIVITY
25
Proportion of px identified correctly by the test as not having the disease
DIAGNOSTIC SPECIFICITY
26
TYPES OF ANALYTICAL ERRORS
* SYSTEMATIC ERRORS * RANDOM ERRORS
27
Errors within test system or method
SYSTEMATIC ERRORS
28
Occur without prediction or regularity
RANDOM ERRORS
28
SOURCES OF ANALYTICAL ERRORS
* Pre-analytical errors * Post-analytical errors
29
INTERNAL QUALITY CONTROL
* Control sample * Calibrators and Standards
30
Pre-analytical errors
Wrong tubes, wrong px identification, wrong labeling, improper transportation
31
Specially prepared specimen treated as a px specimen
Control sample
32
o Adjust instrumentation o Define a standard curve from which patient’s result are read
Calibrators and Standards
32
Provide proficiency surveys
EXTERNAL QUALITY CONTROL
32
Monitor accuracy of individual laboratories
EXTERNAL QUALITY CONTROL