PRELIM LEC: QUALITY CONTROL AND QUALITY ASSURANCE IN HEMATOLOGY

Question 1

Is the broader concept, encompassing
preanalytical, analytical, and postanalytical
variables

Answer 1

QUALITY ASSURANCE

Question 2

Coordinated effort to organize laboratory activities

Answer 2

QUALITY ASSURANCE

Question 2

Control and monitor

Answer 2

QUALITY ASSURANCE

Question 3

Provide best service to patient and doctor

Answer 3

QUALITY ASSURANCE

Question 4

Evaluate and monitor the accuracy and
precision of test performance over time

Answer 4

QUALITY CONTROL

Question 5

To detect errors

Answer 5

QUALITY CONTROL

Question 6

Same matrix as px specimen

Answer 6

CONTROL

Question 7

Predetermined assay value

Answer 7

CONTROL

Question 8

To identify for any contamination

Answer 8

CONTROL

Question 9

Essentially pure form

Answer 9

PRIMARY STANDARD

Question 10

Calibrate instrument

Answer 10

PRIMARY STANDARD

Question 11

Time-consuming

Answer 11

PRIMARY STANDARD

Question 11

Certified reference material

Answer 11

PRIMARY STANDARD

Question 12

Fixed and known composition

Answer 12

PRIMARY STANDARD

Question 13

Analyte concentration ascertained by reference to a primary standard

Answer 13

SECONDARY STANDARD

Question 14

Preserved human or surrogate cell
suspension

Answer 14

CALIBRATOR

Question 15

Closeness of results obtained from repeated analysis of same specimen

Answer 15

PRECISION

Question 16

Closeness to the true or actual value

Answer 16

ACCURACY

Question 17

Reproducibility

Answer 17

PRECISION

Question 18

Assess change

Answer 18

DELTA CHECKS

Question 19

Compare results from spx analysis with result of previous spx

Answer 19

DELTA CHECKS

Question 20

Same analyte, same patient

Answer 20

DELTA CHECKS

Question 21

Extent to which a method is able to maintain
accuracy and precision over time

Answer 21

RELIABILITY

Question 22

Reference range

Answer 22

REFERENCE INTERVAL

Question 23

Range of values of analyte in health individuals

Answer 23

REFERENCE INTERVAL

Question 24

Proportion of px with the disease with positive result

Answer 24

DIAGNOSTIC SENSITIVITY

Question 25

Proportion of px identified correctly by the
test as not having the disease

Answer 25

DIAGNOSTIC SPECIFICITY

Question 26

TYPES OF ANALYTICAL ERRORS

Answer 26

• SYSTEMATIC ERRORS
• RANDOM ERRORS

Question 27

Errors within test system or method

Answer 27

SYSTEMATIC ERRORS

Question 28

Occur without prediction or
regularity

Answer 28

RANDOM ERRORS

Question 28

SOURCES OF ANALYTICAL ERRORS

Answer 28

• Pre-analytical errors
• Post-analytical errors

Question 29

INTERNAL QUALITY CONTROL

Answer 29

• Control sample
• Calibrators and Standards

Question 30

Pre-analytical errors

Answer 30

Wrong tubes, wrong px
identification, wrong labeling,
improper transportation

Question 31

Specially prepared specimen
treated as a px specimen

Answer 31

Control sample

Question 32

o Adjust instrumentation
o Define a standard curve from which
patient’s result are read

Answer 32

Calibrators and Standards

Question 32

Provide proficiency surveys

Answer 32

EXTERNAL QUALITY CONTROL

Question 32

Monitor accuracy of individual laboratories

Answer 32

EXTERNAL QUALITY CONTROL