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Pharmacology > Pregnancy Teratogens > Flashcards

Pregnancy Teratogens Flashcards

1
Q

warfarin - quite a list

A

saddle nose, retarded growth, defects of limbs, eyes, CNS

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2
Q

corticosteroids - clue starts with a c

A

cleft palate and cataract

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3
Q

phenytoin (funny tone) - anti seizure drug

A

cleft palate/mouth, microcephaly, mental retardation

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4
Q

use of valproate

A

epileptic drug - neural tube defects

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5
Q

carbamazepine

A

fetal head retardation

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6
Q

aminoglycosides - what is at the sides of your face

A

deafness

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7
Q

tetracycline - cycling for too long has its detriments. What are they?

A

staining of bones and teeth, thin tooth enamel, impaired bone growth

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8
Q

ethanol

A

fetal alcohol syndrome

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9
Q

breastfeeding is contraindicated in these 2 drugs

A

anticancer

radioactive substances

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10
Q

cabergoline rhymes with dopamine - what is its action?

A

direct inhibitory effect on prolactin

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11
Q

name the 5 substances that inhibit lactation peripherally

A 
alcohol
amphetamine
anabolic steroids
LSD
Nicotine
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12
Q

clozapine

A

agranulocytosis

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13
Q

aspirin (aspireyen)

A

Reye’s syndrome

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14
Q

atenolol should be avoided when breastfeeding. Why

A

causes bradycardia, and lethargy

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15
Q

indomethacin causes a premature closure of what?

A

PDA

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16
Q

avoid amiodarone at all costs. Why?

A

growth retardation, neonatal hypothyroidism, premature birth

17
Q

Name the drugs in category D (9)

A 
aminoglycosides
enalapril
amiodarone
tetracyclines
atenolol
warfarin
phenytoin
carbamazepine and valproate
18
Q

HMG-COA REDUCTASE

A

avoid at all costs

19
Q

category X drugs

A

etretinate (retinoids)

20
Q

neonatal jaundice is caused by which drug?

A

co-trimoxazole

21
Q

INSTI is contraindicated in the first trimester of pregnancy. Why?

A

Neural tube defects

Pharmacology (11 decks)

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