Gout Drugs Flashcards

1
Q

risk factors for gout

A

excessive alcohol, purine rich diet, thiazide diuretics, aspirin, cyclosporin, metabolic syndrome, hypertension, CCF, HPT

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2
Q

first line therapy of nsaids

A

ibuprofen

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3
Q

Harry Bought Nancy Flowers Dude! - adverse effects of NSAIDS

A
hepatotoxicity
bronchoconstriction
nephrotoxicity
fluid retention
dyspepsia
ulceration
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4
Q

WHY do we avoid aspirin?

A

Causes uric acid retention

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5
Q

3 drugs used for acute gout attack

A

NSAIDS, colchicine, prednisone

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6
Q

You can use colchine elsewhere. Where?

A
gout arthritis
pseudo gout
osteoarthritis
pericarditis
atherosclerosis
FMF
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7
Q

where is colchicine contraindicated?

A

RENAL IMPAIRMENT

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8
Q

when do you use corticosteroids?

A

when colchicine and NSAIDS are contraindicated

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9
Q

3 drugs for chronic gout

A

allopurinol, probenacid, citrus acid

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10
Q

where is probenacid contraindicated?

A

urolithiasis, nephrolithiasis, renal impairment

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