Gout Drugs Flashcards
1
Q
risk factors for gout
A
excessive alcohol, purine rich diet, thiazide diuretics, aspirin, cyclosporin, metabolic syndrome, hypertension, CCF, HPT
2
Q
first line therapy of nsaids
A
ibuprofen
3
Q
Harry Bought Nancy Flowers Dude! - adverse effects of NSAIDS
A
hepatotoxicity bronchoconstriction nephrotoxicity fluid retention dyspepsia ulceration
4
Q
WHY do we avoid aspirin?
A
Causes uric acid retention
5
Q
3 drugs used for acute gout attack
A
NSAIDS, colchicine, prednisone
6
Q
You can use colchine elsewhere. Where?
A
gout arthritis pseudo gout osteoarthritis pericarditis atherosclerosis FMF
7
Q
where is colchicine contraindicated?
A
RENAL IMPAIRMENT
8
Q
when do you use corticosteroids?
A
when colchicine and NSAIDS are contraindicated
9
Q
3 drugs for chronic gout
A
allopurinol, probenacid, citrus acid
10
Q
where is probenacid contraindicated?
A
urolithiasis, nephrolithiasis, renal impairment