Pregnancy and Kidney Disease- Das Flashcards

1
Q

key anatomical change to kidney during pregnancy

A

changes to renal pelvis

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2
Q

normal creatinine in patient who is pregnant means what

A

a problem; it should decline

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3
Q

in _____, glucose can still be in urine w/out exceeding renal threshold

A

pregnancy

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4
Q

what threshold is decreased during pregnancy

A

threshold for AVP/ADH release

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5
Q

in a pregnant patient with CKD, what risk increases dramatically

A

risk for preeclampsia

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6
Q

advanced CKD (severe) has what serum creatinine

A

> 2.4

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7
Q

as serum creatinine gets higher, ______ in pregnancy increases

A

problems

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8
Q

as serum creatinine increases during pregnancy, what decreases

A

fetal growth

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9
Q

first step in assessment of fetal well-being

A

non-stress test

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10
Q

2nd step to assess fetal well-being

A

ultrasonic (amniotic fluid, fetal breathing and movements)

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11
Q

how to assess fetal umbilical artery vascular resistance

A

umbilical artery doppler assessment

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12
Q

what is a major risk factor for complications during pregnancy

A

HTN

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13
Q

4 types of HTN seen in pregnancy

A

chronic HTN
gestational HTN
pre-eclampsia
white coat HTN

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14
Q

sometimes during the progression of pregnancy there is a natural decline in what

A

blood pressure

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15
Q

what happens if you reduce bp too much in pregnant patient

A

fetal growth is impaired

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16
Q

if you dont control bp= higher frequency of severe maternal ____

A

HTN

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17
Q

if you achieve a bp goal of ______ = better pregnancy outcomes

18
Q

what medication used for HTN is contraindicated in pregnancy

A

ACEIs and ARBs

19
Q

least risk of pregnancy complications with HbA1c of ____

20
Q

target bp for pregnant patient w/ diabetes and HTN and proteinuria

21
Q

4 maternal/neonatal outcomes for pregnant patient with diabetes and HTN

A

preeclampsia
renal impairement
microvascular disease
neonatal outcomes poor

22
Q

what medication to start to prevent preeclampsia

23
Q

main thing to do for managing bp and bg for pregnant patient

A

reassure the patient

24
Q

pregnant pt has worsening lower extremity edema and protein in urine; what med to give

25
what not to give pregnant patient with nephrotic syndrome
statins
26
what does nephrotic syndrome predispose pregnant patient to
thrombotic events (lose antithrombin III)
27
this is a likely result of preeclampsia and pt has N/V and RUQ pain
AKI
28
what is difficult to diagnose
superimposed preeclampsia
29
what 2 biomarkers are helpful in detecting preeclampsia
placenta growth factor (PlGF) and tyrosine-kinase 1
30
what drug will help in fetal lung development
corticosteroid
31
what drug is administered for neuroprotection for fetus
Mg sulfate
32
pregnant patient with lupus nephritis and CKD should be taking what med
not mycophenolate but azathioprine
33
peak in ____ hormone and ovulation must occur for pt to conceive
LH
34
this drug has a negative impact on fertility
cyclophosphamide
35
can pt on dialysis conceive
yes
36
can pt receiving kidney transplant conceive
yes 1 year after transplant
37
increase in hemodialysis hours= _______
live births
38
dont let pt lie on back while undergoing dialysis b/c compression of _____ on IVC can cause HTN
uterus
39
risk remains high in patient with________ but they can still conceive if kidney function is good
kidney transplant
40
immunosuppressor that blocks calcineurin
Tacrolimus
41
immunosuppressor used instead of mycophenolate or cyclophosphamide
Aziathioprine
42
what other immunosuppressor can be used but just monitor for gestational diabetes
prednisone