Neoplasia of Urinary Tract- Herrera

Question 1

most common renal tumor in adults

Answer 1

renal cell carcinoma

Question 2

to Rx renal cell carcinoma

Answer 2

Bevacizumab
removal of mass

Question 3

most common form of renal cell carcinoma

Answer 3

conventional (clear cell) RCC

Question 4

usually seen in older adults
arises from PCT

Answer 4

conventional (clear cell) RCC

Question 5

has yellow, hemorrhagic appearance!!!

Answer 5

conventional (clear cell) RCC

Question 6

what are the “clear cells” seen on microscopy made of

Answer 6

lipids and glycogen

Question 7

patient presents w/ painless hematuria
might have endocrine sx’s

Answer 7

RCC

Question 8

prognosis for RCC that has renal vein invasion

Answer 8

BAD

Question 9

RCC commonly metastasizes to:

Answer 9

lungs
bones
other kidney

Question 10

very characteristic of what

Answer 10

RCC clear cell (yellow and hemorrhagic)

Question 11

hemorrhaging

Answer 11

RCC (clear cell)

Question 12

characteristic of what

Answer 12

RCC (Clear cell)

Question 13

pools of glycogen

Answer 13

RCC (clear cell)

Question 14

10-15% of renal cell carcinomas
polysomy 7,17,16

Answer 14

papillary type

Question 15

what polysomy for papillary type RCC

Answer 15

polysomy 7

Question 16

5% of RCC

Answer 16

chromophobe type

Question 17

well defined border (clear cell)
perinuclear halo
mitochondria

Answer 17

chromophobe type RCC

Question 18

type of RCC that originates from DCT, unlike the others

Answer 18

chromophobe type

Question 19

brown means? type of RCC?

Answer 19

mitochondria; chromophobe type

Question 20

perinuclear halos
well defined cytoplasmic membrane

Answer 20

chromophobe type RCC

Question 21

prognosis of RCC w/ sarcomatoid areas

Answer 21

very poor

Question 22

white and pearly

Answer 22

RCC w/ sarcomatoid area

Question 23

Answer 23

sarcomatoid area RCC

Question 24

staging of RCC if confined to kidney

Answer 24

stage I

Question 25

stage of RCC w/ perirenal fat but confined to Gerota's fascia

Answer 25

stage 2

Question 26

stage of RCC with renal vein/IVC involvement

Answer 26

stage 3

Question 27

stage of RCC with adjacent organs involved

Answer 27

stage 4

Question 28

type of RCC

Answer 28

clear cell

Question 29

prognosis of thrombus of renal vein

Answer 29

poor

Question 30

worst prognostic indicator of RCC

Answer 30

renal vein involvement

Question 31

children arises from renal blastema tissue painless hematuria

Answer 31

Wilms' tumor

Question 32

wilms' tumor is a ____

Answer 32

nephroblastoma

Question 33

child with large abd mass and painless hematuria

Answer 33

wilms' tumor

Question 34

prognosis of wilms' tumor

Answer 34

great

Question 35

no hemorrhaging or necrosis

Answer 35

wilms' tumor

Question 36

this tumor shows blue under microscope

Answer 36

Wilms' tumor

Question 37

what can also be associated with Wilms tumor that clinician needs to examine

Answer 37

genetics

Question 38

survival rate for Wilms' tumor

Answer 38

high (80-90%)

Question 39

what lines urinary tract

Answer 39

urothelium (transitional epithelium)

Question 40

normal # of layers for urothelium

Answer 40

8-10

Question 41

of layers you will see when there is a tumor of urothelium

Answer 41

>10

Question 42

most common bladder tumor

Answer 42

urothelial carcinomas

Question 43

5% of bladder tumors are ____

Answer 43

squamous cell carcinomas

Question 44

painless hematuria papillary lesions papillary carcinomas on microscope

Answer 44

urothelial cell carcinomas

Question 45

papillary lesion that is lined by 8-10 layers

Answer 45

papilloma

Question 46

urothelium lined with 20 + layers

Answer 46

urothelial carcinoma

Question 47

painless hematuria smoke + aniline dye exposure

Answer 47

transitional cell carcinoma (urothelial)

Question 48

experiences "field effect" on microscopy (urothelium proliferated)

Answer 48

transitional cell(urothelial) carcinoma of pelvis

Question 49

Answer 49

small papillary urothelial carcinoma

Question 50

tumor invading what

Answer 50

ureteral wall

Question 51

aniline dye smoking

Answer 51

bladder carcinomas (urothelial)

Question 52

multifocality (diff. locations of urothelium) recurrence many are superficial

Answer 52

bladder carcinomas

Question 53

localized to epithelium

Answer 53

in situ

Question 54

of layers cells

Answer 54

of layers normal cells atypical urothelial carcinoma in situ

Question 55

Answer 55

urothelial carcinoma in situ- clinging variant

Question 56

tumor of bladder

Answer 56

urothelial carcinoma

Question 57

85% confined to bladder hematuria

Answer 57

urothelial carcinoma of bladder

Question 58

uremia from bilateral ureteral obstruction

Answer 58

common cause of death of urothelial carcinoma of bladder

Question 59

rare in the US poor prognosis late presentation

Answer 59

squamous cell carcinoma of bladder

Question 60

invasion of muscularis propria

Answer 60

poor prognosis of bladder cancer

Question 61

type of bladder carcinoma that is usually super invasive into muscularis propria

Answer 61

squamous cell carcinoma

Question 62

to treat urothelial carcinomas

Answer 62

resection chemo

Question 63

tumor of proximal urethra

Answer 63

urothelial carcinoma

Question 64

tumor of distal urethra

Answer 64

squamous cell carcinoma

Question 65

more common in females bleeding and dysuria

Answer 65

urethral carcinoma

Question 66

painful or uncomfortable urination

Answer 66

dysuria

Question 67

ulcer, weeping, could be painful circumcision prevents this

Answer 67

squamous cell carcinoma of penis

Question 68

location is glans penis and inguinal lymph nodes can be affected

Answer 68

squamous cell carcinoma of the penis

Question 69

Answer 69

squamous cell carcinoma of the penis

Question 70

Answer 70

squamous cell carcinoma of the penis

Question 71

Answer 71

squamous cell carcinoma of the penis