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URN Biweekly 2 > Neoplasia of Urinary Tract- Herrera > Flashcards

Neoplasia of Urinary Tract- Herrera Flashcards

1
Q

most common renal tumor in adults

A

renal cell carcinoma

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2
Q

to Rx renal cell carcinoma

A

Bevacizumab
removal of mass

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3
Q

most common form of renal cell carcinoma

A

conventional (clear cell) RCC

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4
Q

usually seen in older adults
arises from PCT

A

conventional (clear cell) RCC

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5
Q

has yellow, hemorrhagic appearance!!!

A

conventional (clear cell) RCC

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6
Q

what are the “clear cells” seen on microscopy made of

A

lipids and glycogen

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7
Q

patient presents w/ painless hematuria
might have endocrine sx’s

A

RCC

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8
Q

prognosis for RCC that has renal vein invasion

A

BAD

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9
Q

RCC commonly metastasizes to:

A

lungs
bones
other kidney

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10
Q

very characteristic of what

A

RCC clear cell (yellow and hemorrhagic)

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11
Q

hemorrhaging

A

RCC (clear cell)

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12
Q

characteristic of what

A

RCC (Clear cell)

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13
Q

pools of glycogen

A

RCC (clear cell)

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14
Q

10-15% of renal cell carcinomas
polysomy 7,17,16

A

papillary type

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15
Q

what polysomy for papillary type RCC

A

polysomy 7

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16
Q

5% of RCC

A

chromophobe type

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17
Q

well defined border (clear cell)
perinuclear halo
mitochondria

A

chromophobe type RCC

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18
Q

type of RCC that originates from DCT, unlike the others

A

chromophobe type

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19
Q

brown means? type of RCC?

A

mitochondria; chromophobe type

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20
Q

perinuclear halos
well defined cytoplasmic membrane

A

chromophobe type RCC

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21
Q

prognosis of RCC w/ sarcomatoid areas

A

very poor

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22
Q

white and pearly

A

RCC w/ sarcomatoid area

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23
Q
A

sarcomatoid area RCC

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24
Q

staging of RCC if confined to kidney

A

stage I

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25
Q

stage of RCC w/ perirenal fat but confined to Gerota’s fascia

A

stage 2

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26
Q

stage of RCC with renal vein/IVC involvement

A

stage 3

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27
Q

stage of RCC with adjacent organs involved

A

stage 4

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28
Q

type of RCC

A

clear cell

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29
Q

prognosis of thrombus of renal vein

A

poor

30
Q

worst prognostic indicator of RCC

A

renal vein involvement

31
Q

children
arises from renal blastema tissue
painless hematuria

A

Wilms’ tumor

32
Q

wilms’ tumor is a ____

A

nephroblastoma

33
Q

child with large abd mass and painless hematuria

A

wilms’ tumor

34
Q

prognosis of wilms’ tumor

A

great

35
Q

no hemorrhaging or necrosis

A

wilms’ tumor

36
Q

this tumor shows blue under microscope

A

Wilms’ tumor

37
Q

what can also be associated with Wilms tumor that clinician needs to examine

A

genetics

38
Q

survival rate for Wilms’ tumor

A

high (80-90%)

39
Q

what lines urinary tract

A

urothelium (transitional epithelium)

40
Q

normal # of layers for urothelium

A

8-10

41
Q

of layers you will see when there is a tumor of urothelium

A

> 10

42
Q

most common bladder tumor

A

urothelial carcinomas

43
Q

5% of bladder tumors are ____

A

squamous cell carcinomas

44
Q

painless hematuria
papillary lesions
papillary carcinomas on microscope

A

urothelial cell carcinomas

45
Q

papillary lesion that is lined by 8-10 layers

A

papilloma

46
Q

urothelium lined with 20 + layers

A

urothelial carcinoma

47
Q

painless hematuria
smoke + aniline dye exposure

A

transitional cell carcinoma
(urothelial)

48
Q

experiences “field effect” on microscopy (urothelium proliferated)

A

transitional cell(urothelial) carcinoma of pelvis

49
Q
A

small papillary urothelial carcinoma

50
Q

tumor invading what

A

ureteral wall

51
Q

aniline dye
smoking

A

bladder carcinomas
(urothelial)

52
Q

multifocality (diff. locations of urothelium)
recurrence
many are superficial

A

bladder carcinomas

53
Q

localized to epithelium

A

in situ

54
Q

of layers
cells

A

of layers normal
cells atypical
urothelial carcinoma in situ

55
Q
A

urothelial carcinoma in situ- clinging variant

56
Q

tumor of bladder

A

urothelial carcinoma

57
Q

85% confined to bladder
hematuria

A

urothelial carcinoma of bladder

58
Q

uremia from bilateral ureteral obstruction

A

common cause of death of urothelial carcinoma of bladder

59
Q

rare in the US
poor prognosis
late presentation

A

squamous cell carcinoma of bladder

60
Q

invasion of muscularis propria

A

poor prognosis of bladder cancer

61
Q

type of bladder carcinoma that is usually super invasive into muscularis propria

A

squamous cell carcinoma

62
Q

to treat urothelial carcinomas

A

resection
chemo

63
Q

tumor of proximal urethra

A

urothelial carcinoma

64
Q

tumor of distal urethra

A

squamous cell carcinoma

65
Q

more common in females
bleeding and dysuria

A

urethral carcinoma

66
Q

painful or uncomfortable urination

A

dysuria

67
Q

ulcer, weeping, could be painful
circumcision prevents this

A

squamous cell carcinoma of penis

68
Q

location is glans penis and inguinal lymph nodes can be affected

A

squamous cell carcinoma of the penis

69
Q
A

squamous cell carcinoma of the penis

70
Q
A

squamous cell carcinoma of the penis

71
Q
A

squamous cell carcinoma of the penis

URN Biweekly 2 (15 decks)

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