pregnancy Flashcards
cat C—suspect to cause malformation Y/N
N
cat X—should be avoded even if there is a possibility of pregnancy Y/N
Y
Drawbacks and misunderstandings ab the TGA categorey
Does not apply to the breastfeeding
Does not cover off-label use
Does not cover different dose form
Does not take pregnancy stage into consideration
Drugs from the same category do not carry the same risk
Is not a hierarchical system (cat B does not necessarily safer than cat C)
The info is not updated (even more data available, the cat assigned still remains the same)
Manufacturers are allowed to apply for stricter cat (PI—not necessarily align with the assigned category)
Not apply to all conditions (cannot tell the severity of one condition remain untreated)
In Aus we date the pregancy from
the last period
why there is no risk for wk1 and wk2
no even conceived
the more severe form of morning sickness is called
HG
sx of HG
unable to drink or eat
weight loss
how to assess ?
PUQE
pregnancy unique quantification of emesis
score above 13 in PUQE suggests
HG
pharmacological advice on managing morning sickness (1st line)
doxylamine (combine w vit B6—best effect )
metoclopramide (S3—combine w paracetamol not recommended / S4 )
second line
ondansetron
if it is not effective, what should we do ？
discontinue before chaning to the other one
what’s the first lin tx for heartburn and reflux during pregnancy
antiacid
what can cause constipation during pregnancy ?
change in progesterone level
iron supplement / poor fibre intake
try to avoid stimulant laxative during pregancy
Y
