Pregnancy Flashcards
Best and safest therapy for Htn in pregnant women
Labetalol
Methyl Dopa
Nifedipine
Group B streptococcus (GBS) therapy for pregnant woman
Ampicillin penicillin
Cefazolin
If allergic to B lactam
Erythromycin
Clindamycin
Milk production hormone
Prolactin
Most likely to inhibit lactation
Progesterone
Drug passes in milk
Diazepam
Fenastride in pregnancy
Adverse fetal effect
Genital abnormality
Hypospaidias
Monophasic contraceptive
Constant dose of estrogen & progesterone
Enalapril
Unsafe in pregnancy
FDA pregnancy safety categories
Category A
Safe
Control study show no risk
FDA pregnancy safety categories
Category B
Safe.
No evidence of risk in humans.
Animal studies may show risk or not. No risk in humans. If no animal studies than human studies have no risk.
FDA pregnancy safety categories
Category C
Risky
Risk can’t be ruled out.
Human studies are lacking and animal studies show fetal risk.
Only to be used when benefits outweigh risks.
FDA pregnancy safety categories
Category D
Clear Evidence of risk.
FDA pregnancy safety categories
Category X
Contraindicated.
No benefit can warrant their use
Common Category X drugs
Valproate Methotrexate Leflunomide Ribavirin Triazolam Bosentan Aliskiren Levonorgestrel, ulipristal, misoprostol, oxytocin (emergency contraceptive) Griseofulvin Isotretinoin Methylene blue Riociguat
Common Category D drugs
Antimicrobials
Aminoglycosides, sulfamethoxazole, tetracycline, antifungals, primaquine hydroxychloroquin
Neurological drugs
Phenytoin, carbamazepine, benzodiazepines, pentobarbital, lithium, topiramate,
Mg Sulphate (despite being grug.of choice for aclampsia)
CVS Amiodarone, Atenolol, ACE inhibitors, losartan, valsartan Aspirin Edoxaban WARFARIN
Miscellaneous Cortisone, Mycophenolate mofetil, penicillamine, methimazole, propylthiouracil, potassium iodide, hydroxyurea, Bismuth sulphate (3rd tri only) Cyclophosphamide Ibuprofen, Meloxicam Tamoxifen
