Miscellaneous 4

Question 1

Lithium

Answer 1

Narrow therapeutic index

For mania

Question 2

What decrease the effect of warfarin

Answer 2

Antibiotics

Vitamin k

Question 3

Itraconazole requires acidic pH for optimal dissolution

Answer 3

Take it with food

Acid release in stomach

Question 4

Aromatase inhibitor in breast cancer treatment

Answer 4

Anastrozole

Question 5

À1 adrenoreceptors

Answer 5

High bp

Question 6

Most common cause of drug instability

Answer 6

Oxidation

Question 7

Metoclopramide main target for antiemetic effect

Answer 7

Chemoreceptor trigger zone

Question 8

Oseltamivir active metabolite

Answer 8

Has OH group at the extreme left side

Question 9

Breast enlargement in man taking bp meds.

Which med is it

Answer 9

Spironolactone

Aldosterone antagonist

Question 10

Bioisoster of ropibacaine

Answer 10

Levobupvicaine

Question 11

67 yr old man
Tremors etc
Parkinson's suspect
Levodopa along with compound to lower required dose of Levodopa
Which compound?

Answer 11

Carbidopa

A combo is Sinemet

Question 12

Side effect of short half life hypnotics

Answer 12

Tolerance

Question 13

Drug Vd is 35L in 70kg man

Answer 13

Lipid soluble drug

Question 14

Physiochemical characteristics of a drug decreses its transdermal penetration

Answer 14

High melting point

Question 15

Liquid dissolve liquid

Answer 15

Miscibility