Miscellaneous 2

Question 1

PEG conjugate added on drugs to

Answer 1

Prolong half life

Question 2

Xalatan

Answer 2

Latanoprost a prostaglandin analog for open angle glaucoma & occular Hypertension

Question 3

Biophysiological approach of health

Answer 3

Broad view that attributes outcome to the variable interactions of biological factors psychological factors and social factors

Question 4

Hormone that maintains water conc in body

Answer 4

Vasopressin

Question 5

Pregnant female in labor with GBS infection. Penicillin resistant and also Clindamycin and erythromycin resistant.
Now what?

Answer 5

Vancomycin

Order of drugs for GBS inf
Penicillin G
Ampicillin
Clindamycin erythromycin
Vancomycin
Cephalosporins

Question 6

Concept on which most public health studies are based on?

Answer 6

Primary prevention

Question 7

Role of small nuclear sn RNA in protein synthesis

Answer 7

Modifies mRNA molecules

Question 8

Function of colipase

Answer 8

Co enzyme for action of lipase in presence of bile acids

Question 9

Purines nitrogenous base

Answer 9

Adenine guanine

Question 10

Pyrimidine base

Answer 10

Thymine cytosine uracil (RNA)

Question 11

65 ur old patient with osteomalacia.
Numbness, tingling and burning in extremities.
Which IV Ca supplement?

Answer 11

Ca Gluconate

Question 12

Acetylcysteine

Answer 12

Mucolytic

Also N acetyl cysteine is antidote of paracetamol

Question 13

Sterilizing ophthalmic solution

Answer 13

Autoclave 15 min

Question 14

Steady state conc

Answer 14

After 5 half lives

Question 15

Aesculus hippocastanum

Horse Chestnut

Answer 15

Hemorrhoids
Bronchitis
Venous problems
Dysentery

Question 16

Pharmacokinetic parameter that estimates renal function

Answer 16

Creatinine clearance

Question 17

Biphosphonate use

Answer 17

Osteonecrosis of jaw

This class of drugs prevents loss of bone density.
Used for osteoporosis
Inhibit osteoclastic bone resorption

Alendronate
Ibandronate
Risedronate
Palmidronate
Etidronate
Zoledrinic acid

Question 18

Antihyperthyroid drug causing Agranulocytosis

Answer 18

Propylthiouracil

Question 19

Pregnancy NSAIDs intake risk

Answer 19

Uncontrolled Bleeding in neonate
Renal failure in neonate
Low levels of amniotic fluid around the baby and complications

Question 20

Sennoside B

Answer 20

Anthraquinone
Active metabolite of sennoside A & B for laxative effect

Rheinanthrone is also laxative but not linked by o glycoside bond. A dianthrone

Question 21

Anthraquinone

Answer 21

Aglycon moeity woth o glycoside bond
Colorants
Laxative
Antimicrobials
Anti inflammatory

Constipation, arthritis, MS, cancer

Question 22

Active metabolite of primidone

Answer 22

Phenobarbital

Question 23

L Dopa

Answer 23

Levodopa
Parkinson’s
Crosses BBB and converted to dopamine

Question 24

No of half life and steady state conc

Answer 24

No of t½ %age Css

3. 32. 90%
4. 32. 95%
5. 65. 99%

Time for achieving 90% Css = t½ x 3.32

Question 25

Biopharm formula

Answer 25

Css= Q/Cl

Cl= Ke x Vd

Ke= 0.693/t½