Miscellaneous 2 Flashcards
PEG conjugate added on drugs to
Prolong half life
Xalatan
Latanoprost a prostaglandin analog for open angle glaucoma & occular Hypertension
Biophysiological approach of health
Broad view that attributes outcome to the variable interactions of biological factors psychological factors and social factors
Hormone that maintains water conc in body
Vasopressin
Pregnant female in labor with GBS infection. Penicillin resistant and also Clindamycin and erythromycin resistant.
Now what?
Vancomycin
Order of drugs for GBS inf Penicillin G Ampicillin Clindamycin erythromycin Vancomycin Cephalosporins
Concept on which most public health studies are based on?
Primary prevention
Role of small nuclear sn RNA in protein synthesis
Modifies mRNA molecules
Function of colipase
Co enzyme for action of lipase in presence of bile acids
Purines nitrogenous base
Adenine guanine
Pyrimidine base
Thymine cytosine uracil (RNA)
65 ur old patient with osteomalacia.
Numbness, tingling and burning in extremities.
Which IV Ca supplement?
Ca Gluconate
Acetylcysteine
Mucolytic
Also N acetyl cysteine is antidote of paracetamol
Sterilizing ophthalmic solution
Autoclave 15 min
Steady state conc
After 5 half lives
Aesculus hippocastanum
Horse Chestnut
Hemorrhoids
Bronchitis
Venous problems
Dysentery
Pharmacokinetic parameter that estimates renal function
Creatinine clearance
Biphosphonate use
Osteonecrosis of jaw
This class of drugs prevents loss of bone density.
Used for osteoporosis
Inhibit osteoclastic bone resorption
Alendronate Ibandronate Risedronate Palmidronate Etidronate Zoledrinic acid
Antihyperthyroid drug causing Agranulocytosis
Propylthiouracil
Pregnancy NSAIDs intake risk
Uncontrolled Bleeding in neonate
Renal failure in neonate
Low levels of amniotic fluid around the baby and complications
Sennoside B
Anthraquinone
Active metabolite of sennoside A & B for laxative effect
Rheinanthrone is also laxative but not linked by o glycoside bond. A dianthrone
Anthraquinone
Aglycon moeity woth o glycoside bond Colorants Laxative Antimicrobials Anti inflammatory
Constipation, arthritis, MS, cancer
Active metabolite of primidone
Phenobarbital
L Dopa
Levodopa
Parkinson’s
Crosses BBB and converted to dopamine
No of half life and steady state conc
No of t½ %age Css
- 90%
- 95%
- 99%
Time for achieving 90% Css = t½ x 3.32
Biopharm formula
Css= Q/Cl
Cl= Ke x Vd
Ke= 0.693/t½